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[特发性三叉神经痛及三叉神经神经外科手术后角膜敏感性的定量测定]

[Quantitative determination of corneal sensitivity in idiopathic trigeminal neuralgia and after neurosurgical interventions on the trigeminal nerve].

作者信息

Ackermann-Körner M, Draeger J

机构信息

Universitäts-Augenklinik Hamburg.

出版信息

Klin Monbl Augenheilkd. 1991 Aug;199(2):84-90. doi: 10.1055/s-2008-1046053.

Abstract

The purpose of our study was to determine, by use of the electronic Draeger esthesiometer in quantitative, reproductive measurements, the corneal sensitivity in 55 patients with medically treated idiopathic trigeminal neuralgia before and after surgical treatment of the trigeminal nerve and root. 37 patients were included in a prospective study with measurements before and after glycerol rhizotomy, radiofrequency rhizotomy and microvascular decompression (MVD) of the trigeminal root. Moreover, 18 patients were examined retrospectively 7 to 17 years after retrogasserian rhizotomy according to Spiller/Frazier. Corneal sensitivity was determined by the mean value of 3 measurements in each of 5 positions on both eyes. Evaluation of data leads to the following conclusions: In case of neuralgia in the V1 and V2 divisions, corneal sensitivity may decrease without any clinical manifestation. The hypothesis that V2 contributes to corneal innervation got further evidence. Microvascular decompression may lead to a severe decrease of corneal sensitivity. In terms of complications concerning sensory loss of cornea, radiofrequency rhizotomy was the less risky treatment, followed by glycerol rhizotomy, MVD and the retrogasserian rhizotomy according to Spiller/Frazier. Sensitivity affected by prior medical or surgical treatment does not necessarily decrease by further surgical therapy. Postoperatively up to six weeks, corneal sensitivity remained almost the same as shortly after surgical procedure. Keratitis was observed in only one case retrospectively.

摘要

我们研究的目的是,通过使用电子Draeger感觉测量仪进行定量的重复性测量,来确定55例经药物治疗的原发性三叉神经痛患者在三叉神经及神经根手术治疗前后的角膜敏感性。37例患者纳入前瞻性研究,测量甘油神经根切断术、射频神经根切断术和三叉神经根微血管减压术(MVD)前后的情况。此外,对18例根据Spiller/Frazier法行半月节后根切断术7至17年的患者进行回顾性检查。通过测量双眼5个位置中每个位置的3次测量平均值来确定角膜敏感性。数据评估得出以下结论:在V1和V2分支神经痛的情况下,角膜敏感性可能会降低而无任何临床表现。V2参与角膜神经支配的假说得到了进一步证据。微血管减压术可能导致角膜敏感性严重降低。就角膜感觉丧失的并发症而言,射频神经根切断术是风险较小的治疗方法,其次是甘油神经根切断术、MVD和根据Spiller/Frazier法行的半月节后根切断术。先前的药物或手术治疗所影响的敏感性不一定会因进一步的手术治疗而降低。术后长达六周,角膜敏感性几乎与手术后不久相同。回顾性观察仅1例发生角膜炎。

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