使用铊-201单光子发射计算机断层扫描（SPECT）对肺癌患者进行验证。
Validation of single-photon emission computed tomography (SPECT) using thallium-201 in patients with lung cancer.
作者信息
Ishibashi M, Honda N, Yoshioka F, Yoshii T, Nomura Y, Takahashi K, Nagayasu O, Sato M, Fujimoto K, Umezaki N
机构信息
Department of Radiology, Kurume University School of Medicine, Japan.
出版信息
Kurume Med J. 1991;38(2):87-92. doi: 10.2739/kurumemedj.38.87.
To evaluate the primary site, pulmonary hilar, and mediastinal lesions in patients with lung cancer, thallium-201 using single-photon emission computed tomography (SPECT) was used as a tumor agent. The study population consisted of 7 patients (5 men and 2 women), aged 57 to 82 years (mean 68). Tl-201 tomography imaged positive at the primary site in all patients with lung cancer. The images demonstrated the tumor and/or mediastinal lymph nodes that were greater than 2.0cm. In particular, each tomograms facilitated the identification of the Tl-201 increased uptake in proportion to primary site. The short waiting period after injection with Tl-201 clearly offers a major advantage over alternative tumor imaging agents, such as Ga-67 or radiolabeled monoclonal antibodies. Furthermore, Tl-201 SPECT may be useful to detect the tumor and/or mediastinal lymph nodes in patients with lung cancer.
为评估肺癌患者的原发部位、肺门及纵隔病变，将201铊单光子发射计算机断层扫描（SPECT）用作肿瘤显像剂。研究对象包括7例患者（5例男性和2例女性），年龄在57至82岁之间（平均68岁）。201铊断层扫描在所有肺癌患者的原发部位均显示阳性。图像显示了肿瘤和/或直径大于2.0厘米的纵隔淋巴结。特别是，每个断层图像有助于识别与原发部位成比例增加的201铊摄取。注射201铊后等待时间短，显然比其他肿瘤显像剂（如67镓或放射性标记单克隆抗体）具有更大优势。此外，201铊SPECT可能有助于检测肺癌患者的肿瘤和/或纵隔淋巴结。
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