Alsaad Khaled O, Serra Stefano, Chetty Runjan
Department of Laboratory Medicine and Pathobiology, University of Toronto and University Health Network, Toronto, Ontario M5G 2C4, Canada
World J Gastroenterol. 2009 Jul 21;15(27):3431-3. doi: 10.3748/wjg.15.3431.
Goblet cell carcinoid is an uncommon primary tumor of the vermiform appendix, characterized by dual endocrine and glandular differentiation. Whether goblet cell carcinoid represents a morphological variant of appendiceal classical carcinoid or a mucin-producing adenocarcinoma is a matter of conjecture. Rare cases of goblet cell carcinoid with other concomitant appendiceal epithelial neoplasms have been documented. In this report, we describe a rare case of combined appendiceal goblet cell carcinoid and mucinous cystadenoma, and discuss the possible histopathogenesis of this combination.
杯状细胞类癌是一种罕见的阑尾原发性肿瘤,其特征为具有内分泌和腺管双重分化。杯状细胞类癌究竟是阑尾经典类癌的一种形态学变异,还是一种产生黏液的腺癌,目前尚无定论。已有文献记载了罕见的杯状细胞类癌合并其他阑尾上皮性肿瘤的病例。在本报告中,我们描述了一例罕见的阑尾杯状细胞类癌合并黏液性囊腺瘤的病例,并探讨了这种组合可能的组织病理学发生机制。