巴基斯坦和沙特患者霍奇金淋巴瘤组织学表现的比较。

Nagi A H, Al-Menawy L A, Naveed I A, Sami W

Department of Pathology, University of Health Sciences, Lahore, Pakistan.

J Ayub Med Coll Abbottabad. 2008 Jul-Sep;20(3):66-9.

BACKGROUND

Hodgkin's disease (HD) is a relatively rare lymphoma that affects younger as well as older persons. It is reported in the Western as well as Asian studies that HD is a rare disease in developing world. It is commoner in males in most of the countries and shows a bimodal pattern of age. The commonest subtype is nodular sclerosis in the west and mixed cellularity in the eastern and developing countries. The present study compares eight years' data of HD as regard age, sex, site of anatomical presentation and subtypes according to WHO classification among Pakistani and Saudi patients.

METHODS

This retrospective comparative study included 211 cases of HD from various institutions of Lahore, Pakistan; and 78 cases retrieved from the data of King Abdul Aziz Hospital and Oncology Centre, Jeddah, Saudi Arabia.

RESULTS

The analysis of both data of HD showed lack of bimodal age pattern and was common among younger age. Male was the dominating sex. Cervical group of lymph nodes was the commonest presenting site. Mixed cellularity HD (MCHD) was the commonest subtype among Pakistani patients whereas Nodular Sclerotic HD (NSHD) was more common among Saudis.

CONCLUSION

A comparison of the pattern of Pakistani and Saudi data of HD showed lack of bimodality in both. The male sex predominated. Morphologically the MCHD and NSHD were the commonest subtypes in Pakistani & Saudi patients respectively.

背景

霍奇金淋巴瘤（HD）是一种相对罕见的淋巴瘤，可影响年轻人和老年人。西方及亚洲的研究报道称，HD在发展中世界是一种罕见疾病。在大多数国家，HD在男性中更为常见，且呈现双峰年龄模式。在西方，最常见的亚型是结节硬化型，而在东方和发展中国家则是混合细胞型。本研究比较了巴基斯坦和沙特患者中八年的HD数据，涉及年龄、性别、解剖学表现部位以及根据世界卫生组织分类的亚型。