Boop F A, Chadduck W M
Department of Neurosurgery, University of Arkansas for Medical Sciences, Little Rock.
Neurosurgery. 1991 Nov;29(5):785-7; discussion 788. doi: 10.1097/00006123-199111000-00026.
The role of adhesions in the retethering of the neural elements after surgical treatment of spinal dysraphism has produced refinements in the technique of the closure of the neural tube. Silastic, because of its relative inert property, has been used for duraplasty, but a few reports of late complications of hemorrhage or fibrotic capsule formation have caused concern over its use. We report 33 patients with the following diagnoses--eight spinal lipomyelomeningoceles, three myelomeningoceles, six symptomatic Chiari II malformations, seven tethered cords, six spinal cord tumors, two diastematomyelia, and one cerebellar astrocytoma--in whom Silastic dural grafts were used to prevent the adherence of neural structures to the overlying tissues. Our surgical technique is presented here. The patients have been observed for up to 6 years. Only one became infected, was treated with antibiotics without graft removal, and has remained without sequelae for over 3 years. One had an incidental pseudomeningocele that was noted on follow-up magnetic resonance imaging scan that was not clinically apparent. There have been no hemorrhages, leakage of cerebrospinal fluid, nor other complications from using nonreinforced Silastic sheeting. In one patient, Dacron-reinforced Silastic was used and, upon reexploration, a marked fibroblastic response was noted. A review of the literature suggests that fibrotic complications are related to this Dacron-reinforced Silastic. The hemorrhagic complications that were reported occurred in instances where Silastic grafts were large and no technical modifications were made preventively. We conclude that the use of nonreinforced Silastic dural grafts, with appropriate technical modifications in surgical technique, is safe and may prevent retethering of neural tissues in a variety of neurosurgical lesions.
在脊柱裂手术治疗后,粘连在神经组织再栓系过程中所起的作用促使神经管闭合技术得到了改进。硅橡胶因其相对惰性的特性,已被用于硬脑膜成形术,但有几例关于出血或纤维囊形成等晚期并发症的报道引发了对其使用的担忧。我们报告了33例患者,诊断如下:8例脊髓脊膜膨出脂肪瘤、3例脊髓脊膜膨出、6例有症状的Chiari II型畸形、7例脊髓栓系、6例脊髓肿瘤、2例脊髓纵裂以及1例小脑星形细胞瘤,在这些患者中使用了硅橡胶硬脑膜移植物来防止神经结构与上方组织粘连。在此介绍我们的手术技术。对这些患者进行了长达6年的观察。仅1例发生感染,经抗生素治疗未取出移植物,至今3年多无后遗症。1例在随访磁共振成像扫描时发现有偶然的假性脑脊膜膨出,临床未表现出明显症状。使用未加固的硅橡胶片未出现出血、脑脊液漏或其他并发症。1例患者使用了涤纶加固的硅橡胶,再次探查时发现有明显的成纤维细胞反应。文献回顾表明,纤维化并发症与这种涤纶加固的硅橡胶有关。所报道的出血并发症发生在硅橡胶移植物较大且未进行预防性技术改良的情况下。我们得出结论,使用未加固的硅橡胶硬脑膜移植物,并在手术技术上进行适当的改良,是安全的,且可能预防多种神经外科病变中神经组织的再栓系。