Giurgescu Carmen
Department of Women, Children, and Family Health Science, College of Nursing, University of Illinois at Chicago, 845 S. Damen, Chicago, IL 60612, USA.
J Obstet Gynecol Neonatal Nurs. 2009 Jul-Aug;38(4):377-90. doi: 10.1111/j.1552-6909.2009.01034.x.
To examine the evidence related to the relationship between maternal cortisol levels and preterm birth.
A search of Medline, PubMed, and Cumulative Index of Nursing and Allied Health Literature was conducted using the keywords preterm birth, preterm delivery, premature birth, and cortisol.
Fifteen studies published in English were selected based on the inclusion criteria. There were no limitations on the dates of publication.
The data extracted were related to the gestational age at collection of biological samples, time of day at collection, and differences in cortisol levels between preterm and full-term groups.
The majority of the studies suggested that maternal cortisol levels are related to preterm birth. Women with higher levels of cortisol had higher risk of having a preterm birth.
Researchers can use the findings of this review to develop future studies that examine the relationship between cortisol levels and preterm birth. Health care providers need to assess pregnant women's stress levels more closely and provide appropriate referrals and treatment to ensure that any actions that may possibly lower stress are being taken to reduce the likelihood of preterm birth.
探讨与孕妇皮质醇水平和早产之间关系相关的证据。
使用关键词早产、早产分娩、早产和皮质醇对医学索引数据库（Medline）、医学期刊数据库（PubMed）以及护理与联合健康文献累积索引数据库进行检索。
根据纳入标准选取了15篇英文发表的研究。对发表日期没有限制。
提取的数据涉及采集生物样本时的孕周、采集时间以及早产组和足月组之间皮质醇水平的差异。
大多数研究表明孕妇皮质醇水平与早产有关。皮质醇水平较高的女性早产风险更高。
研究人员可利用本综述的结果开展未来研究，以探讨皮质醇水平与早产之间的关系。医疗保健提供者需要更密切地评估孕妇的压力水平，并提供适当的转诊和治疗，以确保采取一切可能降低压力的措施来减少早产的可能性。
