Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada.
Diabetes Obes Metab. 2009 Sep;11(9):836-43. doi: 10.1111/j.1463-1326.2009.01050.x. Epub 2009 Jul 10.
To examine the impact of two different lifestyle programmes on cardiovascular health and glycaemic control among people with type 2 diabetes.
A two-phase 24-week randomized trial. During the first phase, participants were to increase daily steps using a pedometer. At week 12, participants were randomly allocated to either an enhanced lifestyle programme (ELP) targeting walking speed or a basic lifestyle programme (BLP) targeting total daily steps. Both programmes focused on increasing the intake of low glycaemic index foods but utilized different goal setting strategies. Clinical measurements were completed at baseline, week 12 and week 24. Principal outcomes were change in resting pulse rate (PR) and glycated haemoglobin A1c (A1c) between week 12 and week 24 compared between groups using analysis of covariance.
Forty-one participants [mean +/- s.d. : age = 56.5 +/- 7.2 years, body mass index (BMI) = 32.7 +/- 6.1 kg/m(2)] were randomized. After 12 weeks, we observed an increase in average total daily steps of 1688 (95% confidence interval: 330-3040, [corrected] p = 0.02). Weight, BMI and systolic and diastolic blood pressure improved (p < 0.01 for all). No changes were observed for energy intake. At week 24, those in the ELP had a lower resting PR (71 +/- 12 b.p.m.) compared with those in the BLP (78 +/- 12 b.p.m.) (adjusted p = 0.03), while no group differences for total daily steps or glycaemic control were observed.
Improvements in cardiovascular health can be expected following a pedometer-based lifestyle modification programme that progresses from walking more to walking faster.
研究两种不同生活方式方案对 2 型糖尿病患者心血管健康和血糖控制的影响。
一项两阶段 24 周随机试验。在第一阶段,参与者使用计步器增加日常步数。在第 12 周,参与者被随机分配到以提高步行速度为目标的强化生活方式方案(ELP)或以增加每日总步数为目标的基本生活方式方案(BLP)。两种方案均侧重于增加低升糖指数食物的摄入,但采用了不同的目标设定策略。在基线、第 12 周和第 24 周完成临床测量。主要结局是组间比较第 12 周至第 24 周期间静息脉搏率(PR)和糖化血红蛋白 A1c(A1c)的变化,采用协方差分析。
41 名参与者[平均 +/- 标准差:年龄=56.5 +/- 7.2 岁,体重指数(BMI)=32.7 +/- 6.1 kg/m(2)]被随机分配。12 周后,我们观察到平均每日总步数增加了 1688 步(95%置信区间:330-3040,[校正]p=0.02)。体重、BMI、收缩压和舒张压均有所改善(所有 p<0.01)。能量摄入没有变化。第 24 周时,ELP 组的静息 PR(71 +/- 12 b.p.m.)低于 BLP 组(78 +/- 12 b.p.m.)(调整后 p=0.03),而两组在每日总步数或血糖控制方面均无差异。
在基于计步器的生活方式改变方案后,可预期心血管健康会得到改善,该方案从增加步数进展到提高步速。