Chen Ji-Jun, Gao Jian-Rong, Han Liang, Jia Jian-Hong, Sheng Wei-Jian, Li Yu-Jing
Zhejiang University of Technology, Hang Zhou, PR China.
Carbohydr Res. 2009 Oct 12;344(15):2056-9. doi: 10.1016/j.carres.2009.06.028. Epub 2009 Jun 26.
Peracetylated 2-deoxy-d-erythro-pentose (2-deoxy-d-ribose) was synthesized through the acetylation of 2-deoxy-d-ribose with acetic anhydride in pyridine, and the products (including all four ring forms) exist in form of either a white solid or a syrup. A single crystal of 1,3,4-tri-O-acetyl-2-deoxy-beta-d-erythro-pentopyranose was obtained from the syrup and its structure was determined by X-ray diffraction. The crystal adopts the (1)C(4) conformation, presenting an orthorhombic system, space group P2(1)2(1)2(1) with Z=4, unit cell dimensions a=7.2274 (3)A, b=8.0938 (5)A, and c=22.0517 (11)A.
通过在吡啶中用乙酸酐对2-脱氧-D-核糖进行乙酰化反应合成了全乙酰化的2-脱氧-D-赤藓戊糖（2-脱氧-D-核糖），产物（包括所有四种环状形式）以白色固体或糖浆形式存在。从糖浆中获得了1,3,4-三-O-乙酰基-2-脱氧-β-D-赤藓戊吡喃糖的单晶，并通过X射线衍射确定了其结构。该晶体采用(1)C(4)构象，呈正交晶系，空间群为P2(1)2(1)2(1)，Z = 4，晶胞参数a = 7.2274 (3)Å，b = 8.0938 (5)Å，c = 22.0517 (11)Å。
