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保留部分完整的自体窦管交界的主动脉窦成形术。

Valve-sparing aortic root remodeling with partial preservation of the intact native aortic sinuses.

机构信息

Department of Cardiac and Thoracic Vascular Surgery, University of Luebeck, Luebeck, Germany.

出版信息

Eur J Cardiothorac Surg. 2009 Sep;36(3):589-91. doi: 10.1016/j.ejcts.2009.05.036. Epub 2009 Jul 18.

Abstract

There are certain aortic root pathologies where only one or two of the aortic sinuses are diseased. We aimed to evaluate our mid-term results after a partial remodeling of the aortic root. A total of 220 patients underwent a valve-sparing operation at our institution. In 29 patients (mean age: 62+/-10 years), two (n=22) or one (n=7) native aortic sinuses were preserved. Operative indication was type A aortic dissection (n=12) or aortic root aneurysm (n=17). Preoperative aortic valve regurgitation was 1.8+/-1.1 grades. Mean follow-up time was 46+/-32 months. At the latest follow-up, 23 patients were alive and asymptomatic. One ascending aorta re-operation was observed due to late aortic graft infection. Echocardiographic measurements at latest follow-up were excellent: aortic regurgitation: 0.6+/-0.5 grades; aortic valve area: 2.7+/-0.7 cm2; aortic root dimensions: anulus 23+/-3mm, sinus 34+/-5mm, sinotubular junction 28+/-5mm and ascending aorta: 30+/-2mm. Longitudinal analysis revealed no development of clinically significant aortic regurgitation (<0.03 grades per year). However, in contrast to the group that underwent complete remodeling (n=108), a significant dilatation at sinus and ST junction (STJ) level could be observed in the partial remodeling group over time (0.35 and 0.48 mm per year, respectively). This should be taken into consideration when applying this technique in patients operated on an elective basis.

摘要

存在某些主动脉根部病变,只有一个或两个主动脉窦受累。我们旨在评估我们对主动脉根部部分重塑的中期结果。共有 220 例患者在我们的机构接受了瓣膜保留手术。在 29 例患者中(平均年龄:62+/-10 岁),有两个(n=22)或一个(n=7)保留了原生主动脉窦。手术指征为 A 型主动脉夹层(n=12)或主动脉根部瘤(n=17)。术前主动脉瓣反流为 1.8+/-1.1 级。平均随访时间为 46+/-32 个月。在最近的随访中,23 例患者存活且无症状。因晚期主动脉移植物感染观察到 1 例升主动脉再次手术。最新随访时的超声心动图测量结果极佳:主动脉瓣反流:0.6+/-0.5 级;主动脉瓣口面积:2.7+/-0.7cm2;主动脉根部尺寸:瓣环 23+/-3mm,窦 34+/-5mm,窦管交界 28+/-5mm 和升主动脉:30+/-2mm。纵向分析显示,无临床意义的主动脉瓣反流(每年<0.03 级)进展。然而,与完全重塑组(n=108)相比,部分重塑组在随访过程中可以观察到窦和窦管交界水平的显著扩张(每年分别为 0.35mm 和 0.48mm)。在择期手术患者中应用该技术时应考虑到这一点。

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