David T E, Feindel C M, Bos J
Division of Cardiovascular Surgery, University of Toronto, Ontario, Canada.
J Thorac Cardiovasc Surg. 1995 Feb;109(2):345-51; discussion 351-2. doi: 10.1016/S0022-5223(95)70396-9.
Patients with aneurysms of the ascending aorta or aortic root frequently have aortic insufficiency despite normal aortic leaflets. The aortic valve dysfunction is caused by dilatation of the sinotubular junction, distortion or dilatation of the sinuses of Valsalva, annuloaortic ectasia, or a combination of these problems. In the case of annuloaortic ectasia, reconstruction of the aortic root is performed by reimplanting the aortic valve in a tubular Dacron graft (reimplantation). In the case of mild or no annuloaortic ectasia, reconstruction of the aortic root is performed by correcting the dilated sinotubular junction and replacement of the aortic sinuses if they are also dilated with an appropriately tailored Dacron graft (remodeling). From July 1989 to March 1994, 45 patients have had either reimplantation of the aortic valve (19 patients) or remodeling of the aortic root (26 patients). Fourteen patients had Marfan's syndrome, 11 had acute and five had chronic type A aortic dissection, and nine also had transverse arch aneurysm. There were two operative deaths, both in the remodeling group. One patient who had reimplantation needed composite replacement of the aortic valve and ascending aorta because of persistent aortic insufficiency after the repair. A young patient with Marfan's syndrome had progressive aortic valve dysfunction during a growth spurt and had aortic valve replacement 2 years after the initial operation. No other valve-related complication has occurred. The remaining 41 patients have only mild or no aortic insufficiency, and the repair remains stable from 1 to 58 months, mean 18 months. These two types of aortic valve reconstruction have provided excellent clinical results in carefully selected adult patients.
升主动脉或主动脉根部动脉瘤患者,即使主动脉瓣叶正常,也常伴有主动脉瓣关闭不全。主动脉瓣功能障碍是由窦管交界扩张、主动脉窦扭曲或扩张、主动脉瓣环扩张症,或这些问题的组合引起的。对于主动脉瓣环扩张症,通过将主动脉瓣重新植入涤纶人工血管(再植入术)来进行主动脉根部重建。对于轻度或无主动脉瓣环扩张症的情况,通过纠正扩张的窦管交界并在主动脉窦也扩张时用适当剪裁的涤纶人工血管替换主动脉窦(重塑术)来进行主动脉根部重建。1989年7月至1994年3月,45例患者接受了主动脉瓣再植入术(19例)或主动脉根部重塑术(26例)。14例患者患有马方综合征,11例患有急性A型主动脉夹层,5例患有慢性A型主动脉夹层,9例还患有横弓动脉瘤。有2例手术死亡,均在重塑术组。1例接受再植入术的患者因修复后持续存在主动脉瓣关闭不全而需要进行主动脉瓣和升主动脉的复合置换。1例患有马方综合征的年轻患者在生长突增期间出现进行性主动脉瓣功能障碍,并在初次手术后2年进行了主动脉瓣置换。未发生其他与瓣膜相关的并发症。其余41例患者仅伴有轻度或无主动脉瓣关闭不全,修复在1至58个月内保持稳定,平均18个月。这两种主动脉瓣重建方法在精心挑选的成年患者中取得了出色的临床效果。