Department of Radiology, St. Elisabeth Ziekenhuis, Tilburg, the Netherlands.
AJNR Am J Neuroradiol. 2009 Oct;30(9):1646-8. doi: 10.3174/ajnr.A1673. Epub 2009 Jul 17.
Coiling is increasingly used as treatment for intracranial aneurysms with favorable short-term outcome. Concern exists about long-term reopening and the inherent risk of recurrent subarachnoid hemorrhage (SAH), and long-term imaging follow-up is advocated. It is unknown for how long and how often coiled aneurysms need to be followed and what subgroups carry a higher or lower risk for reopening. Recently, new data have become available that concern the designation of an optimal long-term follow-up protocol. Three studies focused on a special subgroup, the coiled aneurysms that are adequately occluded at 6 months. This subgroup comprises about 80% of all coiled aneurysms. In these aneurysms, the risk of reopening that needs retreatment during the next 5-10 years is very low. In addition, the risk of recurrent SAH is almost zero, even lower than that after clipping. Within the first 5 years after coiling, the incidence of the development of de novo aneurysms or enlargement of existing untreated aneurysms is low, with an extremely low risk of recurrent SAH from these aneurysms. These data suggest that aneurysms that are adequately occluded at 6 months after coiling, in general, do not need prolonged imaging follow-up in the next 5-10 years. More data are needed to identify possible subgroups with adequately occluded coiled aneurysms at 6 months that behave differently on longer follow-up, such as giant aneurysms, partially thrombosed aneurysms, or patients with a positive family history.
弹簧圈栓塞术越来越多地用于治疗颅内动脉瘤,且具有良好的短期疗效。但长期再通以及由此导致的复发性蛛网膜下腔出血(subarachnoid hemorrhage,SAH)的固有风险令人担忧,因此提倡长期影像学随访。目前尚不清楚需要对弹簧圈栓塞的动脉瘤进行多长时间和多频繁的随访,以及哪些亚组的再通风险更高或更低。最近,有新数据涉及到最佳长期随访方案的指定。有三项研究集中在一个特殊的亚组,即 6 个月时充分闭塞的弹簧圈栓塞动脉瘤。该亚组约占所有弹簧圈栓塞动脉瘤的 80%。在这些动脉瘤中,在接下来的 5-10 年内需要再次治疗的再通风险非常低。此外,复发性 SAH 的风险几乎为零,甚至低于夹闭后。在弹簧圈栓塞后的前 5 年内,新发动脉瘤的发展或未治疗的现有动脉瘤增大的发生率较低,这些动脉瘤发生复发性 SAH 的风险极低。这些数据表明,在 6 个月后充分闭塞的动脉瘤通常不需要在接下来的 5-10 年内进行长期影像学随访。需要更多的数据来识别可能存在的亚组,这些亚组中的动脉瘤在 6 个月时充分闭塞,但在更长时间的随访中表现不同,例如巨大动脉瘤、部分血栓形成的动脉瘤或有阳性家族史的患者。