Andrade Ana Regina Coelho de, Grossi Maria Aparecida de Faria, Bührer-Sékula Samira, Antunes Carlos Maurício Figueiredo
Graduate program in Health Sciences: Infectology and Tropical Medicine of the Federal University of Minas Gerais, MG, Brazil.
Rev Soc Bras Med Trop. 2008;41 Suppl 2:56-9. doi: 10.1590/s0037-86822008000700012.
Leprosy is a public health problem in Brazil. Epidemiological control actions are based on the diagnosis and treatment of leprosy patients and household contact surveillance. Serological tests for leprosy could identify from among the contacts those at greater risk of developing leprosy in the future. ML Flow was administered to 2,840 household contacts of new leprosy cases diagnosed from October 2002 to March 2004, in State of Minas Gerais. ML Flow was positive in 20.5% of leprosy contacts, with high seropositivity among males (22.4%), individuals aged over 15 years-old (21.7%) and individuals in contact with multibacillary cases (23.9%). The chances of a household contact presenting a seropositive test was related to household contact with a multibacillary index case (OR=1.75), age over 15 years-old (OR=1.38) and male gender (OR=1.25). Follow-up of these contacts is necessary to evaluate the real role of seropositivity in the development of leprosy disease.
麻风病在巴西是一个公共卫生问题。流行病学控制行动基于麻风病患者的诊断和治疗以及家庭接触者监测。麻风病血清学检测可以从接触者中识别出未来患麻风病风险更高的人群。2002年10月至2004年3月期间，在米纳斯吉拉斯州，对2840名新诊断麻风病病例的家庭接触者进行了ML Flow检测。20.5%的麻风病接触者ML Flow检测呈阳性，男性（22.4%）、15岁以上个体（21.7%）以及与多菌型病例接触的个体（23.9%）的血清阳性率较高。家庭接触者血清检测呈阳性的几率与家庭接触多菌型索引病例（比值比=1.75）、年龄超过15岁（比值比=1.38）以及男性性别（比值比=1.25）有关。对这些接触者进行随访对于评估血清阳性在麻风病发病中的实际作用是必要的。
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