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麻风病患者中ML Flow血清阳性的危险因素。

Risk factors for ML Flow seropositivity in leprosy patients.

作者信息

Grossi Maria Aparecida de Faria, Leboeuf Maria Ana Araújo, Andrade Ana Regina Coelho de, Bührer-Sékula Samira, Antunes Carlos Maurício de Figueiredo

机构信息

Post-graduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.

出版信息

Rev Soc Bras Med Trop. 2008;41 Suppl 2:39-44. doi: 10.1590/s0037-86822008000700009.

Abstract

The early diagnosis of leprosy, its correct classification and the risk factors related to seropositivity have become important for patient treatment and disease control, especially where the responsibility for treatment has been transferred to basic health care centers. This descriptive, exploratory study using logistic regression was undertaken to evaluate the association between the variables of sex, age, mode of detection, number of skin lesions and affected nerves, disability grade and bacilloscopy with the results of the ML Flow serological test in 1,072 new leprosy cases in 13 municipalities in Minas Gerais State. Seropositivity (50.7%) was statistically associated with patients 15 years-old or over (OR:2.6) and those with more than five skin lesions (OR:7.5), more than one affected nerve (OR:2.4) and a positive bacilloscopic index (OR:5.5 for 0<BI<2 and OR:191.2 for BI>or=2), thus contributing to the appropriate classification and treatment of patients.

摘要

麻风病的早期诊断、正确分类以及与血清学阳性相关的危险因素对于患者治疗和疾病控制已变得至关重要,尤其是在治疗责任已转移至基层医疗保健中心的地区。本描述性探索性研究采用逻辑回归方法,旨在评估米纳斯吉拉斯州13个市的1072例新麻风病病例中,性别、年龄、检测方式、皮肤损害数量和受累神经数量、残疾等级以及细菌学检查结果等变量与ML Flow血清学检测结果之间的关联。血清学阳性(50.7%)与15岁及以上患者(比值比:2.6)、皮肤损害超过5处(比值比:7.5)、受累神经超过1条(比值比:2.4)以及细菌学检查指数阳性(0<细菌学检查指数<2时比值比:5.5,细菌学检查指数≥2时比值比:191.2)存在统计学关联,从而有助于对患者进行恰当的分类和治疗。

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