Zienciuk Agnieszka, Szwoch Małgorzata, Raczak Grzegorz
Klinika Kardiologii i Elektroterapii Serca, Gdański Uniwersytet Medyczny, ul. Debinki 7, 80-211 Gdańsk, Poland.
Kardiol Pol. 2009 Jun;67(6):681-4, discussion 685-6.
A case of a 58-year-old woman with occasionally diagnosed persistent atrial fibrillation (AF) is presented. The patient for many years experienced palpitations relived by oral propranolol treatment. After electrical cardioversion of AF to sinus rhythm prolongation of the QTc interval up to 520 ms became evident. Molecular screening of LQTS-related genes revealed the presence of R231S mutation in the KCNQ1 gene.
本文报告一例58岁偶尔被诊断为持续性心房颤动(AF)的女性病例。该患者多年来经历心悸,口服普萘洛尔治疗可缓解。房颤经电复律转为窦性心律后,QTc间期延长至520毫秒变得明显。对长QT综合征(LQTS)相关基因进行分子筛查,发现KCNQ1基因存在R231S突变。