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厌食症和贪食症中存在明显认知障碍的定量证据。

Quantitative evidence for distinct cognitive impairment in anorexia nervosa and bulimia nervosa.

机构信息

Department of Psychology, University of Toronto Scarborough, Toronto, Canada.

出版信息

J Neuropsychol. 2010 Mar;4(Pt 1):89-106. doi: 10.1348/174866409X459674. Epub 2009 Jul 16.

Abstract

It is generally agreed that at least some aspects of abnormal eating behaviour is indeed due in part to disordered cognition. The accumulated literature illustrates cognitive impairment in patients with anorexia nervosa (AN) and bulimia nervosa (BN). Yet beyond being inconsistent, these independent studies also do not reveal the magnitude of impairment within and across studies and fail to give due consideration to the magnitude of impairment so as to understand the severity and breadth of impairment and/or differences in cognitive profiles between patients with AN and BN. Hence, the present review on the subject sought to articulate the magnitude of cognitive impairment in patients with AN and BN by quantitatively synthesizing the existing literature using meta-analytic methodology. The results demonstrate modest evidence of cognitive impairment specific to AN and BN that is related to body mass index in AN in terms of its severity, and is differentially impaired between disorders. Together, these results suggest that disturbed cognition is figural in the presentation of eating disorders and may serve to play an integral role in its cause and maintenance. Implications of these findings with respects to future research are discussed.

摘要

人们普遍认为,某些异常的进食行为确实部分归因于认知障碍。已有的文献表明厌食症(AN)和贪食症(BN)患者存在认知损伤。然而,这些独立的研究不仅结果不一致,而且没有揭示研究内和研究间的损伤程度,也没有充分考虑损伤的严重程度,因此无法理解 AN 和 BN 患者的损伤严重程度和广度,或者认知特征的差异。因此,本综述旨在通过使用荟萃分析方法对现有文献进行定量综合,阐明 AN 和 BN 患者的认知损伤程度。研究结果表明,存在针对 AN 和 BN 的认知损伤的中度证据,其严重程度与 AN 中的体重指数有关,并且在不同疾病之间存在差异。总之,这些结果表明,紊乱的认知是进食障碍表现的一个特征,可能对其病因和维持起着重要作用。就未来研究而言,讨论了这些发现的意义。

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