Adam Julien, Bonnichon Philippe, Vacher-Lavenu Marie-Cécile, Tissier Frédérique
Service d'anatomie pathologique, hôpital Cochin, AP-HP, 75679 Paris cedex 14, France.
Ann Pathol. 2009 Jun;29(3):245-8. doi: 10.1016/j.annpat.2009.03.001. Epub 2009 Jun 13.
Lymphoepithelial cysts are rare lesions of the thyroid, with exceptional bilateral presentation. We report the case of a 62-year-old woman presenting with a multinodular goiter, without associated clinical or biological abnormality. Histological examination demonstrated multiple cysts lined by squamous or respiratory-type epithelium, associated with a dense lymphoid infiltrate. Chronic thyroiditis and numerous solid cell nests were also observed in the adjacent parenchyma. We briefly discuss differential diagnosis and current hypothesis concerning the pathogenesis of these peculiar lesions.
淋巴上皮囊肿是甲状腺的罕见病变,双侧出现的情况极为罕见。我们报告一例62岁女性患者,其表现为多结节性甲状腺肿,无相关临床或生物学异常。组织学检查显示多个囊肿内衬鳞状或呼吸型上皮,伴有密集的淋巴细胞浸润。在相邻的实质中还观察到慢性甲状腺炎和大量实性细胞巢。我们简要讨论了这些特殊病变的鉴别诊断和当前关于其发病机制的假说。