Department of Medical Physics, McGill University Health Centre, Montreal General Hospital, Montreal, QC, Canada.
Phys Med. 2010 Jan;26(1):38-43. doi: 10.1016/j.ejmp.2009.06.002. Epub 2009 Jul 19.
The aim of this study was to use different gamma histogram criteria for the comparison of planned dose with irradiated dose distribution and find that what percent of pixels passing a certain criteria imitate a good quality plan. The dose was calculated for 156 patients by inverse planning optimization using the Corvus treatment planning system. Gafchromic films in combination with 2571 0.6 cm(3) Farmer type ionization chamber and Farmer 2570/1 electrometer from NE Technology were used to measure the delivered dose in solid water phantom. All the measurements were performed on Varian CL21EX linear accelerator (Varian Medical Systems, Palo Alto, CA) fitted with a Millennium 120 leaf collimator. In this study the mean value of the percent of passing pixels within the region of interest under the criterion of 3% DD and 3mm DTA is 90.2+/-7.1% for head and neck cases and 92.2+/-5.8% for non-head and neck cases. If we choose the criteria of 3% DD and 3mm DTA then 96.3% head and neck plans have the percent of passing pixels>or=75% and 95.1% non-head and neck plans have the percent of passing pixels>or=80%. It is evident from the results of this study that the criterion of 5% DD and 3mm DTA with the percent of passing pixels>or=90 for non-head and neck cases while the percent of passing pixels>or=85 for head and neck cases endorse that a plan is good. The results of this study may be useful for other institutions which use verification software and EBT films for patient specific IMRT QA.
本研究旨在使用不同的伽马直方图标准来比较计划剂量与照射剂量分布,并发现通过某个标准的像素百分比模拟了一个好的计划质量。使用 Corvus 治疗计划系统对 156 名患者进行了逆向计划优化计算。Gafchromic 胶片结合 2571 个 0.6cm(3)Farmer 型电离室和来自 NE Technology 的 Farmer 2570/1 静电计用于在固体水模体中测量传递剂量。所有测量均在配备有 Millennium 120 叶准直器的瓦里安 CL21EX 直线加速器(瓦里安医疗系统,帕洛阿尔托,加利福尼亚州)上进行。在这项研究中,在 3%DD 和 3mm DTA 标准下,感兴趣区域内通过像素的平均值为 90.2+/-7.1%,用于头颈部病例,92.2+/-5.8%用于非头颈部病例。如果我们选择 3%DD 和 3mm DTA 的标准,那么 96.3%的头颈部计划有通过像素的百分比>or=75%,95.1%的非头颈部计划有通过像素的百分比>or=80%。从这项研究的结果可以明显看出,对于非头颈部病例,5%DD 和 3mm DTA 的标准为通过像素的百分比>or=90%,而对于头颈部病例,通过像素的百分比>or=85%,这表明计划是良好的。这项研究的结果可能对其他使用验证软件和 EBT 胶片进行患者特定 IMRT QA 的机构有用。