Samolyk Keith A
Global Blood Resources LLC.
Semin Cardiothorac Vasc Anesth. 2009 Jun;13(2):118-21. doi: 10.1177/1089253209339510.
Blood has been described as the most precious and personal substance in the world. Current directions in cardiac surgery are moving away from transfusing donor "Allogeneic" blood products, and towards improving methods of saving and preserving the patient's own "autologous" blood. Nothing else comes close to the natural healing abilities and homeostasis that one's own whole blood offers. No substitute, whether it is human or artificial, will ever work as well with fluid shifts, hemostasis and homeostasis. News reports today commonly feature severe blood shortages and research documenting recognized transfusion risks such as how older stored blood can put heart surgery patients at increased risk and others that point to the morbidity and mortality associated with its use. Therefore the medical community is moving towards more effective blood utilization by minimizing the exposure to donated blood. Current techniques are saving as much as possible of the patient's own blood that might otherwise be mismanaged or lost during surgery. Techniques, such as Ultrafiltration, that quickly concentrate and reinfuse whole blood back to the patient are the best choice. Admission to discharge hemovigilance requires a concerted multidisciplinary team effort with multimodal tools available in the coagulation armamentarium to effectively avoid this form of organ transplant. Improving outcomes and reducing morbidity and mortality in cardiac surgery takes place at the microcirculatory capillary level and with control of Hemostasis. Cardiac teams need to effectively communicate and minimize blood loss and hemodilution and reverse it, for state of the art blood management in Cardiac surgery.
血液被描述为世界上最珍贵和最具个人属性的物质。当前心脏外科手术的发展方向正从输注供体的“异体”血液制品,转向改进保存和留存患者自身“自体”血液的方法。没有什么能比得上自身全血所具备的自然愈合能力和内稳态。无论是人类血液还是人造血液,没有任何替代品能在液体转移、止血和内稳态方面发挥得如此出色。如今的新闻报道经常提及严重的血液短缺,以及研究记录的公认输血风险,比如储存时间较长的血液如何会使心脏手术患者面临更高风险,还有其他一些研究指出了与输血相关的发病率和死亡率。因此,医学界正朝着更有效的血液利用方向发展,尽量减少对捐献血液的接触。当前的技术正在尽可能多地留存患者自身的血液,否则这些血液在手术过程中可能会被管理不善或流失。诸如超滤等能快速浓缩并将全血回输到患者体内的技术是最佳选择。从入院到出院的血液监测需要多学科团队协同努力,利用凝血手段中的多模式工具来有效避免这种器官移植形式。在心脏外科手术中,改善手术效果、降低发病率和死亡率是在微循环毛细血管层面以及通过控制止血来实现的。心脏手术团队需要进行有效沟通,尽量减少失血和血液稀释并予以纠正,以实现心脏外科手术的先进血液管理。