Sherer David M, Dalloul Mudar, Salameh Ghadir, Abulafia Ovadia
From the Department of Obstetrics and Gynecology, the Divisions of Maternal Fetal Medicine, and Gynecologic Oncology, State University of New York, Downstate Medical Center, Brooklyn, New York.
Obstet Gynecol. 2009 Aug;114(2 Pt 2):471-472. doi: 10.1097/AOG.0b013e3181ac4e18.
Methicillin-resistant Staphylococcus aureus (MRSA) is an extremely rare etiology of chorioamnionitis.
A young primigravida, with sickle cell (Hb SS) disease and beta thalassemia presented at 37 weeks of gestation with fever, chills, and lower abdominal pain in the presence of intact fetal membranes, 10 days after recurrent marsupialization of a Bartholin abscess. Overt clinical chorioamnionitis was diagnosed. The patient received intravenous triple antibiotics and delivered by immediate cesarean. Maternal blood, uterine, placental and neonatal nares, external auditory canal, and umbilical cord stump cultures all yielded MRSA. Both the mother and infant received intravenous vancomycin and did well.
Our case and the literature suggest that it may be prudent to consider MRSA when contemplating the possibility of chorioamnionitis in the presence of intact fetal membranes, especially in gravidas with recurrent admissions or minor surgical procedures or who are hospital staff.
耐甲氧西林金黄色葡萄球菌(MRSA)是绒毛膜羊膜炎极为罕见的病因。
一名年轻初产妇,患有镰状细胞(Hb SS)病和β地中海贫血,妊娠37周时出现发热、寒战和下腹部疼痛,胎膜完整,在巴氏腺脓肿反复袋形缝合术后10天。诊断为明显的临床绒毛膜羊膜炎。患者接受静脉三联抗生素治疗,并立即剖宫产分娩。产妇血液、子宫、胎盘以及新生儿鼻腔、外耳道和脐带残端培养物均培养出MRSA。母亲和婴儿均接受静脉万古霉素治疗,情况良好。
我们的病例及文献表明,在胎膜完整且考虑绒毛膜羊膜炎可能性时,尤其是对于反复入院、接受小手术或医院工作人员的孕妇,考虑MRSA可能是谨慎的做法。