Fennema-Notestine Christine
Department of Psychiatry, University of California - San Diego, La Jolla, CA, USA.
Methods Mol Biol. 2009;569:25-32. doi: 10.1007/978-1-59745-524-4_2.
To promote scientific discovery and education, the federated Biomedical Informatics Research Network (BIRN) Data Repository (BDR) supports data storage, sharing, querying, and downloading for the biomedical community, enabling the integration of multiple data resources from a single entry point. The BDR encourages data sharing both for investigators requesting assistance with databasing and informatics infrastructure, and for those wishing to extend the reach of existing data resources to be registered with the BDR. Both approaches rely heavily on data integration and knowledge management techniques, ensuring capabilities for intelligent exploration of diverse data resources that make up the BDR's shared environment. Although the development of the BDR has been driven by BIRN testbeds in the fields of neuroscience and neuroimaging, the infrastructure is flexible and extendable to serve a broad array of disciplines, fueling interdisciplinary studies. For a welcoming environment, the BDR provides simple, straightforward policies and procedures for contributing data and for using available data. Contributing investigators provide information through the BDR Gridsphere-based Portal environment to allow meaningful sharing of their data, and, when relevant, supply documentation for human subjects' protection. The BDR aims to provide a common resource to increase the availability of, and access to, rare data; complex, sizable data; and existing data sharing structures in support of research and education in the scientific and clinical communities.
为促进科学发现与教育,联邦生物医学信息学研究网络(BIRN)数据存储库(BDR)为生物医学领域提供数据存储、共享、查询及下载支持,实现从单一入口点整合多个数据资源。BDR鼓励数据共享,既为那些在数据库和信息学基础设施方面寻求协助的研究人员提供支持,也为那些希望将现有数据资源的覆盖范围扩展至BDR注册范围的人员提供便利。这两种方式都严重依赖数据整合和知识管理技术,确保具备对构成BDR共享环境的各种数据资源进行智能探索的能力。尽管BDR的开发由神经科学和神经成像领域的BIRN测试平台推动,但该基础设施具有灵活性和可扩展性,能够服务于广泛的学科领域,推动跨学科研究。为营造一个友好的环境,BDR提供了简单、直接的数据贡献和使用现有数据的政策与程序。数据贡献研究人员通过基于BDR Gridsphere的门户环境提供信息,以便有意义地共享其数据,并在相关时提供人类受试者保护的文件。BDR旨在提供一个共同资源,以增加稀有数据、复杂的大量数据以及现有数据共享结构的可用性和获取途径,支持科学和临床社区的研究与教育。