Weekes C E, Spiro A, Baldwin C, Whelan K, Thomas J E, Parkin D, Emery P W
Department of Nutrition & Dietetics, Guy's & St Thomas' NHS Foundation Trust, St Thomas' Hospital, London, UK.
J Hum Nutr Diet. 2009 Aug;22(4):324-35. doi: 10.1111/j.1365-277X.2009.00971.x.
The association between malnutrition and poor clinical outcome is well-established, yet most research has focussed on the role of artificial nutritional support in its management. More recently, emphasis has been placed on the provision of adequate nutritional care, including nutritional screening and the routine provision of food and drink. The aim of this literature review is to establish the evidence for the efficacy of interventions that might result in improvements in nutritional and clinical outcomes and costs.
A structured literature review was conducted investigating the role of nutritional care interventions in adults, and their effects on nutritional and clinical outcomes and costs, in all healthcare settings. Ten databases were searched electronically using keywords relating to nutritional care, patient outcomes and healthcare costs. High quality trials were included where available.
Two hundred and ninety-seven papers were identified and reviewed. Of these, only two randomised, controlled trials and six other trials were identified that addressed the major issues. A further 99 addressed some aspects of the provision of nutritional care, although very few formally evaluated nutritional or clinical outcomes and costs.
This review reveals a serious lack of evidence to support interventions designed to improve nutritional care, in particular with reference to their effects on nutritional and clinical outcomes and costs. The review suggests that screening alone may be insufficient to achieve beneficial effects and thus more research is required to determine the most cost-effective interventions in each part of the nutritional care pathway, in a variety of healthcare settings and across all age ranges, to impact upon nutritional and clinical outcomes.
营养不良与不良临床结局之间的关联已得到充分证实,但大多数研究都集中在人工营养支持在其管理中的作用。最近,重点已放在提供充分的营养护理上,包括营养筛查以及常规提供食物和饮料。这篇文献综述的目的是确定可能改善营养和临床结局及成本的干预措施的有效性证据。
进行了一项结构化文献综述,调查营养护理干预措施在所有医疗环境中对成年人的作用及其对营养和临床结局及成本的影响。使用与营养护理、患者结局和医疗成本相关的关键词对十个数据库进行了电子检索。如有高质量试验则纳入。
共识别并审查了297篇论文。其中,仅确定了两项随机对照试验和其他六项试验涉及主要问题。另有99篇涉及营养护理提供的某些方面,尽管很少有正式评估营养或临床结局及成本的。
本综述表明严重缺乏证据支持旨在改善营养护理的干预措施,特别是关于其对营养和临床结局及成本的影响。该综述表明仅筛查可能不足以产生有益效果,因此需要更多研究来确定在各种医疗环境中以及所有年龄段的营养护理路径各环节中最具成本效益的干预措施,以影响营养和临床结局。