Korea Artificial Organ Center, Korea University Medical College, Seoul, Korea.
Artif Organs. 2009 Aug;33(8):627-33. doi: 10.1111/j.1525-1594.2009.00780.x. Epub 2009 Jun 28.
The bellows-type pneumatic ventricular assist device (VAD) generates pneumatic pressure with compression of bellows instead of using an air compressor. This VAD driver has a small volume that is suitable for portable devices. However, improper pneumatic pressure setup can not only cause a lack of adequate flow generation, but also cause durability problems. In this study, a pneumatic pressure regulation system for optimal operation of the bellows-type VAD has been developed. The optimal pneumatic pressure conditions according to various afterload conditions aiming for optimal flow rates were investigated, and an afterload estimation algorithm was developed. The developed regulation system, which consists of a pressure sensor and a two-way solenoid valve, estimates the current afterload and regulates the pneumatic pressure to the optimal point for the current afterload condition. Experiments were performed in a mock circulation system. The afterload estimation algorithm showed sufficient performance with the standard deviation of error, 8.8 mm Hg. The flow rate could be stably regulated with a developed system under various afterload conditions. The shortcoming of a bellows-type VAD could be handled with this simple pressure regulation system.
风箱式气动心室辅助装置（VAD）通过压缩风箱产生气动压力，而不是使用空气压缩机。这种 VAD 驱动器体积小，适合便携式设备。然而，气动压力设置不当不仅会导致流量不足，还会导致耐用性问题。在这项研究中，已经开发出一种用于优化风箱式 VAD 运行的气动压力调节系统。根据各种后负荷条件，针对最佳流量，研究了最佳气动压力条件，并开发了一种后负荷估计算法。该调节系统由压力传感器和双向电磁阀组成，可根据当前的后负荷条件估计当前的后负荷，并将气动压力调节到最佳点。在模拟循环系统中进行了实验。后负荷估计算法的误差标准差为 8.8mmHg，性能良好。在各种后负荷条件下，都可以用开发的系统稳定地调节流量。这种简单的压力调节系统可以解决风箱式 VAD 的缺点。
