School of Psychology, Queen's University Belfast, Belfast BT7 1NN, UK.
Biol Lett. 2009 Dec 23;5(6):743-5. doi: 10.1098/rsbl.2009.0407. Epub 2009 Jul 22.
Single cell recording studies have resulted in a detailed understanding of motion-sensitive neurons in non-human primate visual cortex. However, it is not known to what extent response properties of motion-sensitive neurons in the non-human primate brain mirror response characteristics of motion-sensitive neurons in the human brain. Using a motion adaptation paradigm, the direction aftereffect, we show that changes in the activity of human motion-sensitive neurons to moving dot patterns that differ in dot density bear a strong resemblance to data from macaque monkey. We also show a division-like inhibition between neural populations tuned to opposite directions, which also mirrors neural-inhibitory behaviour in macaque. These findings strongly suggest that motion-sensitive neurons in human and non-human primates share common response and inhibitory characteristics.
单细胞记录研究已经深入了解了非人类灵长类动物视觉皮层中对运动敏感的神经元。然而，目前尚不清楚非人类灵长类动物大脑中对运动敏感的神经元的反应特性在多大程度上反映了人类大脑中对运动敏感的神经元的反应特征。我们使用运动适应范式，即方向后效，表明人类对运动点模式的运动敏感神经元的活动变化与猕猴的实验数据非常相似，这些点模式在点密度上有所不同。我们还展示了对相反方向调谐的神经群体之间类似分叶的抑制，这也反映了猕猴的神经抑制行为。这些发现强烈表明，人类和非人类灵长类动物的运动敏感神经元具有共同的反应和抑制特征。
