State Key Laboratory of Cognitive Neuroscience and Learning, IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
Elife. 2021 Mar 24;10:e61317. doi: 10.7554/eLife.61317.
Human and nonhuman primates are good at identifying an object based on its motion, a task that is believed to be carried out by the ventral visual pathway. However, the neural mechanisms underlying such ability remains unclear. We trained macaque monkeys to do orientation discrimination for motion boundaries (MBs) and recorded neuronal response in area V2 with microelectrode arrays. We found 10.9% of V2 neurons exhibited robust orientation selectivity to MBs, and their responses correlated with monkeys' orientation-discrimination performances. Furthermore, the responses of V2 direction-selective neurons recorded at the same time showed correlated activity with MB neurons for particular MB stimuli, suggesting that these motion-sensitive neurons made specific functional contributions to MB discrimination tasks. Our findings support the view that V2 plays a critical role in MB analysis and may achieve this through a neural circuit within area V2.
人类和非人类灵长类动物善于根据物体的运动来识别物体，据信这一任务是通过腹侧视觉通路来完成的。然而，这种能力的神经机制尚不清楚。我们训练猕猴进行运动边界（MB）的方向辨别，并使用微电极阵列记录 V2 区的神经元反应。我们发现，10.9%的 V2 神经元对 MB 表现出强烈的方向选择性，它们的反应与猴子的方向辨别表现相关。此外，同时记录的 V2 方向选择性神经元的反应与特定 MB 刺激的 MB 神经元表现出相关的活动，表明这些运动敏感神经元对 MB 辨别任务做出了特定的功能贡献。我们的研究结果支持了 V2 在 MB 分析中起着关键作用的观点，并且可能通过 V2 内的神经网络来实现这一点。
