Seifert G, Brocheriou C, Cardesa A, Eveson J W
Institute of Pathology, University of Hamburg, FRG.
Pathol Res Pract. 1990 Oct;186(5):555-81. doi: 10.1016/S0344-0338(11)80220-7.
The principles of the proposed modified WHO Histological Typing of Salivary Gland Tumours are based on the following: 1) The classification of tumours is oriented to the routine work of the practicing surgical pathologists, those who do not see tumours of the salivary glands very often. The inclusion of rare, but clearly defined tumour entities should be helpful to surgical pathologists consulting with clinical specialists. 2) The different types of carcinomas must be distinguished not only by precise histopathological definitions, but also considering differences in prognosis and treatment. For example, the polymorphous low-grade adenocarcinoma and the epithelial-myoepithelial carcinoma are characterized by a relatively good prognosis in contrast to the salivary duct carcinoma. 3) Special points of discussion are: subclassification and grading of carcinomas (e.g. acinic cell carcinoma, mucoepidermoid carcinoma and adenoid cystic carcinoma), the classification of basal cell tumours (basal cell adenoma, basal cell carcinoma, solid type of adenoid cystic carcinoma), malignant tumours in pleomorphic adenomas and the differential diagnosis between primary tumours and metastases.
1）肿瘤分类针对的是外科病理医师的日常工作，这些医师并非经常接触唾液腺肿瘤。纳入罕见但明确界定的肿瘤实体应有助于外科病理医师与临床专科医生进行会诊。2）不同类型的癌不仅必须通过精确的组织病理学定义来区分，还应考虑预后和治疗方面的差异。例如，多形性低度腺癌和上皮-肌上皮癌的预后相对较好，与唾液腺导管癌形成对比。3）讨论的要点包括：癌的亚分类和分级（如腺泡细胞癌、黏液表皮样癌和腺样囊性癌）、基底细胞肿瘤的分类（基底细胞腺瘤、基底细胞癌、实性型腺样囊性癌）、多形性腺瘤中的恶性肿瘤以及原发性肿瘤与转移瘤的鉴别诊断。
