Seifert G
University of Hamburg, Germany.
Eur J Cancer B Oral Oncol. 1992 Jul;28B(1):49-56. doi: 10.1016/0964-1955(92)90013-q.
This report is based upon the Salivary Gland Register in Hamburg and on the second revised edition of the WHO Histological Typing of Salivary Gland Tumours. The group of malignant salivary gland tumours contains carcinomas, malignant non-epithelial tumours, malignant lymphomas and secondary tumours. The various carcinomas are classified in a continuous separate listing because the different types are distinguished not only by histopathology, but also by differences in prognosis and treatment. The term "tumour" is replaced by "carcinoma" in two entities: acinic cell carcinoma and mucoepidermoid carcinoma. New entities are: polymorphous low-grade adenocarcinoma, basal cell adenocarcinoma, salivary duct carcinoma and malignant myoepithelioma. Carcinoma in pleomorphic adenoma can be distinguished as non-invasive and invasive carcinoma, and carcinosarcoma. Malignant non-epithelial tumours are mostly malignant fibrous histiocytoma, malignant schwannoma and rhabdomyosarcoma. The large majority of malignant lymphomas are non-Hodgkin-lymphomas with high differentiation. Many lymphomas are associated with chronic immunosialadenitis (Sjögren's syndrome). Secondary tumours are mostly metastases from primary squamous cell carcinomas or from melanomas of the skin (head and neck area). Haematogeneous metastases are very rare (mainly from lung, kidney or breast).
本报告基于汉堡唾液腺登记册以及世界卫生组织唾液腺肿瘤组织学分类第二修订版。恶性唾液腺肿瘤包括癌、恶性非上皮性肿瘤、恶性淋巴瘤和继发性肿瘤。各种癌被分类在一个连续的单独列表中，因为不同类型不仅通过组织病理学区分，而且在预后和治疗方面也存在差异。在两种实体中，“肿瘤”一词被“癌”取代：腺泡细胞癌和黏液表皮样癌。新的实体包括：多形性低度腺癌、基底细胞腺癌、唾液导管癌和恶性肌上皮瘤。多形性腺瘤中的癌可区分为非侵袭性癌、侵袭性癌和癌肉瘤。恶性非上皮性肿瘤主要是恶性纤维组织细胞瘤、恶性神经鞘瘤和横纹肌肉瘤。绝大多数恶性淋巴瘤是高分化的非霍奇金淋巴瘤。许多淋巴瘤与慢性免疫性涎腺炎（干燥综合征）相关。继发性肿瘤主要是原发性鳞状细胞癌或皮肤（头颈部区域）黑色素瘤的转移瘤。血行转移非常罕见（主要来自肺、肾或乳腺）。
