Klein Joel, Chan Shannon
Division of Infectious Diseases, Alfred I. duPont Hospital for Children, 1600 Rockland Road, Wilmington, DE 19803, USA.
Clin Pediatr (Phila). 2010 Jan;49(1):66-8. doi: 10.1177/0009922809342463. Epub 2009 Jul 23.
Methicillin-resistant Staphylococcus aureus (MRSA) infections and colonization in children have increased in recent years.
This study examined the possible effect of this increase on MRSA isolation from middle ear fluid (MEF) of children.
A retrospective descriptive study was performed using the electronic medical records of children cared for at the Alfred I. duPont Hospital for Children from 2003 to 2007. All MEF isolates obtained at tympanostomy tube placement for recurrent or chronic otitis media or from spontaneous drainage were tabulated and analyzed. Records of children whose MEF grew S aureus comprised our database.
A total of 920 MEF isolates were reviewed, of which 121 patients with S aureus in the MEF were identified. Twenty were excluded per protocol. In the cohort of 101 patients, 76 had methicillin-sensitive Staphylococcus aureus (MSSA; 75.3%) and 25 had MRSA (24.7%).
In this retrospective study, the authors demonstrated that among children with S aureus in the MEF, younger children (<3 years) were more likely to have MRSA.
近年来，耐甲氧西林金黄色葡萄球菌（MRSA）在儿童中的感染和定植有所增加。
本研究探讨了这种增加对从儿童中耳液（MEF）中分离出MRSA的可能影响。
采用回顾性描述性研究，使用2003年至2007年在阿尔弗雷德·I·杜邦儿童医院接受治疗的儿童的电子病历。将所有在鼓膜置管治疗复发性或慢性中耳炎时或从自发引流中获得的MEF分离株进行列表和分析。MEF中培养出金黄色葡萄球菌的儿童记录构成了我们的数据库。
共审查了920株MEF分离株，其中121例MEF中存在金黄色葡萄球菌的患者被识别出来。根据方案排除20例。在101例患者的队列中，76例患有甲氧西林敏感金黄色葡萄球菌（MSSA；75.3%），25例患有MRSA（24.7%）。
在这项回顾性研究中，作者表明，在MEF中存在金黄色葡萄球菌的儿童中，年龄较小的儿童（<3岁）更有可能感染MRSA。
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