Grässel E, Hoppe U, Rosanowski F
Bereich Medizinische Psychologie und Medizinische Soziologie der Psychiatrischen und Psychotherapeutischen Klinik, Universitätsklinikum Erlangen, Erlangen, Deutschland.
HNO. 2009 Sep;57(9):896-901. doi: 10.1007/s00106-009-1953-9.
Although the voice-related quality of life (VRQOL) questionnaire has proved to be an appropriate diagnostic tool, there are no recommendations on how to grade the score. In this study the VRQOL was graded against the background of health-related quality of life.
A total of 105 patients (56 women and 49 men) aged 49.4+/-16.1 years who presented with dysphonia of benign origin completed a German version of the VRQOL and the SF-36 health survey after giving informed consent. There was an organic disorder in 50%, in 37% a functional disorder and 13% had no disorder.
The only difference between the results of the VRQOL and the SF-36 was in the subscale on social functioning which showed a moderately strong (r(S)=0.40) and highly significant reduction in dysphonic patients (p<0.001). These results were therefore used as an external criterion for the graduation of the VRQOL results. The data suggest that VRQOL values of 0-40 can be classified as "clinically relevant deterioration", values of 41-80 as "no clinically relevant deterioration" and values over 80 as "normal" voice-related quality of life".
The suggested grading system simplifies the assessment of individual VRQOL values. Now their clinical relevance as indication and end-point parameters must be investigated.
尽管嗓音相关生活质量（VRQOL）问卷已被证明是一种合适的诊断工具，但对于如何对分数进行分级尚无建议。在本研究中，VRQOL是在健康相关生活质量的背景下进行分级的。
共有105例年龄为49.4±16.1岁、患有良性发声困难的患者（56名女性和49名男性）在签署知情同意书后完成了德语版的VRQOL和SF-36健康调查。其中50%存在器质性疾病，37%为功能性疾病，13%无疾病。
VRQOL和SF-36结果之间的唯一差异在于社会功能子量表，该量表显示发声困难患者有中度显著降低（r(S)=0.40）且差异极显著（p<0.001）。因此，这些结果被用作VRQOL结果分级的外部标准。数据表明，VRQOL值为0 - 40可归类为“临床相关恶化”，41 - 80为“无临床相关恶化”，超过80为“正常”嗓音相关生活质量。
建议的分级系统简化了个体VRQOL值的评估。现在必须研究它们作为指示和终点参数的临床相关性。
