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脂肪切除术作为一种新的方法,用于将直接自体前臂桡动脉-头静脉内瘘进行二次手术浅表化,以用于血液透析。

Lipectomy as a new approach to secondary procedure superficialization of direct autogenous forearm radial-cephalic arteriovenous accesses for hemodialysis.

作者信息

Bourquelot Pierre, Tawakol Jan Bijan, Gaudric Julien, Natário Ana, Franco Gilbert, Turmel-Rodrigues Luc, Van Laere Olivier, Raynaud Alain

机构信息

Clinique Jouvenet, Paris, France.

出版信息

J Vasc Surg. 2009 Aug;50(2):369-74, 374.e1. doi: 10.1016/j.jvs.2009.03.009.

Abstract

BACKGROUND

The depth of veins can discourage surgeons from creating radial-cephalic arteriovenous accesses for hemodialysis in obese patients. Elevation and tunneled transposition are the two techniques that have been described to superficialize these veins and make them accessible for cannulation. Unfortunately, such manipulation of veins has potential drawbacks. We report lipectomy, a new technique that removes subcutaneous fat and does not mobilize the vein.

METHODS

This single-center prospective study included 49 consecutive patients (17 men, 32 women) who underwent second-stage lipectomy after creation of a radial-cephalic fistula. Mean patient age was 54 years, 36% had diabetes, and the mean body mass index was 31 +/- 5.6 kg/m(2). Subcutaneous fatty tissues were removed after two transverse skin incisions under regional anesthesia and preventive hemostasis. Cannulation was first allowed 1 month later, after clinical and color duplex ultrasound evaluation. Technical success was defined as the ability to remove the fat and to palpate the patent vein immediately under the skin at the end of the operation. Clinical success was defined as the ability to perform at least three consecutive dialysis sessions with two needles. All patients were checked systematically every 6 months by the surgeon.

RESULTS

Technical and clinical success rates were 96% (47 of 49) and 94% (46 of 49), respectively. Mean vein depth decreased from 8 +/- 2 to 3 +/- 1 mm according to duplex ultrasound imaging. The mean vein diameter increased from 6 +/- 1 to 8 +/- 2 mm. In one patient, vein tortuosity that was overlooked required conventional repeat tunneling. One extensive hematoma resulted in loss of the fistula. One patient died before the fistula could be used. Primary patency rates were 71% +/- 7% and 63% +/- 8% at 1 and 3 years, respectively, and secondary patency rates were 98% +/- 2% and 88% +/- 7%. Delayed complications were treated by surgery (n = 7) or by endovascular procedures (n = 10).

CONCLUSION

Lipectomy is a safe, effective, and durable approach to make deep arterialized forearm veins accessible for routine cannulation for hemodialysis in obese patients. It might even be hypothesized that incident obese dialysis patients will eventually have the highest proportion of radial-cephalic fistulas because they often have distal veins that have been preserved by their fat from previous attempts at cannulation for blood sampling or infusion.

摘要

背景

静脉深度可能会使外科医生不愿为肥胖患者建立用于血液透析的桡动脉 - 头静脉通路。抬高和隧道转位是已被描述的两种使这些静脉浅表化并便于插管的技术。不幸的是,这种对静脉的操作存在潜在缺点。我们报告了一种新的技术——脂肪切除术,该技术可去除皮下脂肪且不游离静脉。

方法

这项单中心前瞻性研究纳入了49例连续患者(17例男性,32例女性),他们在建立桡动脉 - 头静脉内瘘后接受了二期脂肪切除术。患者平均年龄为54岁,36%患有糖尿病,平均体重指数为31±5.6kg/m²。在区域麻醉和预防性止血下,通过两个横向皮肤切口切除皮下脂肪组织。在临床和彩色双功超声评估后,1个月后首次允许进行插管。技术成功定义为在手术结束时能够去除脂肪并立即在皮肤下触及通畅的静脉。临床成功定义为能够使用两根针进行至少三次连续的透析治疗。外科医生每6个月对所有患者进行系统检查。

结果

技术成功率和临床成功率分别为96%(49例中的47例)和94%(49例中的46例)。根据双功超声成像,平均静脉深度从8±2mm降至3±1mm。平均静脉直径从6±1mm增加到8±2mm。在1例患者中,一处被忽视的静脉迂曲需要进行传统的再次隧道化处理。1例广泛血肿导致内瘘丧失。1例患者在瘘管可用之前死亡。1年和3年时的初次通畅率分别为71%±7%和63%±8%,二次通畅率分别为98%±2%和88%±7%。延迟并发症通过手术(n = 7)或血管内介入治疗(n = 10)。

结论

脂肪切除术是一种安全、有效且持久的方法,可使肥胖患者深层动脉化的前臂静脉便于进行常规血液透析插管。甚至可以推测,肥胖的新透析患者最终可能拥有最高比例的桡动脉 - 头静脉内瘘,因为他们通常有远端静脉,这些静脉因脂肪而得以保留,此前未因采血或输液插管尝试而受损。

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