Lu Li-Min, Zhang Li, Qu Feng-Li, Lu Hai-Xia, Zhang Xiao-Bing, Wu Zai-Sheng, Huan Shuang-Yan, Wang Qiu-An, Shen Guo-Li, Yu Ru-Qin
State Key Laboratory of Chemical Biosensing & Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, PR China.
Biosens Bioelectron. 2009 Sep 15;25(1):218-23. doi: 10.1016/j.bios.2009.06.041. Epub 2009 Jul 7.
Highly ordered Ni nanowire arrays (NiNWAs) were synthesized for the first time using a template-directed electropolymerization strategy with a nanopore polycarbonate (PC) membrane template, and their morphological characterization were examined by scanning electron microscopy (SEM) and transmission electron microscope (TEM). A NiNWAs based electrode shows very high electrochemical activity for electrocatalytic oxidation of glucose in alkaline medium, which has been utilized as the basis of the fabrication of a nonenzymatic biosensor for electrochemical detection of glucose. The biosensor can be applied to the quantification of glucose with a linear range covering from 5.0x10(-7) to 7.0x10(-3) M, a high sensitivity of 1043 microA mM(-1) cm(-2), and a low detection limit of 1x10(-7) M. The experiment results also showed that the sensor exhibits good reproducibility and long-term stability, as well as high selectivity with no interference from other oxidable species.
首次采用具有纳米孔聚碳酸酯（PC）膜模板的模板导向电聚合策略合成了高度有序的镍纳米线阵列（NiNWAs），并通过扫描电子显微镜（SEM）和透射电子显微镜（TEM）对其形态进行了表征。基于NiNWAs的电极在碱性介质中对葡萄糖的电催化氧化表现出非常高的电化学活性，这已被用作制造用于葡萄糖电化学检测的非酶生物传感器的基础。该生物传感器可用于葡萄糖定量分析，线性范围为5.0×10（-7）至7.0×10（-3）M，灵敏度高达1043 μA mM（-1）cm（-2），检测限低至1×10（-7）M。实验结果还表明，该传感器具有良好的重现性和长期稳定性，以及高选择性，不受其他可氧化物质的干扰。
