肠缺血：形态学特征——II
Intestinal ischemia: morphological features--II.
作者信息
Santacroce S, Nicolardi G, Sinigaglia E, Formosa P, Bartoli F, Veneziani G, Demundo M, Ambrosi A, Santacroce A
机构信息
Istituto di I Patologia Speciale Chirurgica, Università degli Studi di Bari.
出版信息
Boll Soc Ital Biol Sper. 1990 Aug;66(8):747-52.
Superoxide radicals produced during acute intestinal ischemia are biochemically related with the presence of hydrogen peroxyde. In this study we have investigated the distribution of peroxidase-catalase activity, histochemically determined, in the ischemic ileal wall. In the rat, complete arterial and venous occlusion produced a progressive increase in extra-vascular peroxidase-catalase activity with a maximum corresponding to the ileal wall. Probably the tissue peroxidase-catalase activity is related to massive degranulation of polymorphonucleates.
急性肠道缺血期间产生的超氧自由基在生化方面与过氧化氢的存在有关。在本研究中，我们通过组织化学方法研究了缺血性回肠壁中过氧化物酶 - 过氧化氢酶活性的分布。在大鼠中，完全的动静脉闭塞导致血管外过氧化物酶 - 过氧化氢酶活性逐渐增加，最大值出现在回肠壁。组织过氧化物酶 - 过氧化氢酶活性可能与多形核白细胞的大量脱颗粒有关。
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