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Cancer Biol Ther. 2009 Sep;8(17):1659-61. doi: 10.4161/cbt.8.17.9456. Epub 2009 Sep 7.
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Stomatin-like protein 2 inhibits cisplatin-induced apoptosis through MEK/ERK signaling and the mitochondrial apoptosis pathway in cervical cancer cells.质膜内在蛋白 2 通过 MEK/ERK 信号通路和线粒体凋亡通路抑制顺铂诱导的宫颈癌细胞凋亡。
Cancer Sci. 2018 May;109(5):1357-1368. doi: 10.1111/cas.13563. Epub 2018 Apr 24.
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Downregulation of a mitochondria associated protein SLP-2 inhibits tumor cell motility, proliferation and enhances cell sensitivity to chemotherapeutic reagents.下调线粒体相关蛋白 SLP-2 可抑制肿瘤细胞迁移、增殖,并增强细胞对化疗药物的敏感性。
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Stomatin-like protein 2 binds cardiolipin and regulates mitochondrial biogenesis and function.基质蛋白 2 结合心磷脂,调节线粒体生物发生和功能。
Mol Cell Biol. 2011 Sep;31(18):3845-56. doi: 10.1128/MCB.05393-11. Epub 2011 Jul 11.
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[Expression of SLP-2 mRNA in endometrial cancer and its significance].
Zhonghua Fu Chan Ke Za Zhi. 2005 Aug;40(8):553-7.
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SLP-2 negatively modulates mitochondrial sodium-calcium exchange.SLP-2 负向调节线粒体钠钙交换。
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Stomatin-like protein 2 regulates survivin expression in non-small cell lung cancer cells through β-catenin signaling pathway.质膜内在蛋白 2 通过β-连环蛋白信号通路调节非小细胞肺癌细胞中存活素的表达。
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SLP-2 interacts with prohibitins in the mitochondrial inner membrane and contributes to their stability.SLP-2 在线粒体内膜中与抑制素相互作用,并有助于其稳定性。
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Lab Invest. 2013 Jan;93(1):8-19. doi: 10.1038/labinvest.2012.144. Epub 2012 Oct 29.

本文引用的文献

1
Downregulation of a mitochondria associated protein SLP-2 inhibits tumor cell motility, proliferation and enhances cell sensitivity to chemotherapeutic reagents.下调线粒体相关蛋白 SLP-2 可抑制肿瘤细胞迁移、增殖,并增强细胞对化疗药物的敏感性。
Cancer Biol Ther. 2009 Sep;8(17):1651-8. doi: 10.4161/cbt.8.17.9283. Epub 2009 Sep 17.
2
ATP-citrate lyase links cellular metabolism to histone acetylation.ATP-柠檬酸裂解酶将细胞代谢与组蛋白乙酰化联系起来。
Science. 2009 May 22;324(5930):1076-80. doi: 10.1126/science.1164097.
3
Understanding the Warburg effect: the metabolic requirements of cell proliferation.理解瓦伯格效应:细胞增殖的代谢需求。
Science. 2009 May 22;324(5930):1029-33. doi: 10.1126/science.1160809.
4
SLP-2 is required for stress-induced mitochondrial hyperfusion.应激诱导的线粒体过度融合需要SLP-2。
EMBO J. 2009 Jun 3;28(11):1589-600. doi: 10.1038/emboj.2009.89. Epub 2009 Apr 9.
5
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism.c-Myc对miR-23a/b的抑制作用增强了线粒体谷氨酰胺酶的表达及谷氨酰胺代谢。
Nature. 2009 Apr 9;458(7239):762-5. doi: 10.1038/nature07823. Epub 2009 Feb 15.
6
Caenorhabditis elegans drp-1 and fis-2 regulate distinct cell-death execution pathways downstream of ced-3 and independent of ced-9.秀丽隐杆线虫的drp-1和fis-2在ced-3下游调节不同的细胞死亡执行途径,且不依赖于ced-9。
Mol Cell. 2008 Aug 22;31(4):586-597. doi: 10.1016/j.molcel.2008.07.015.
7
Bax- or Bak-induced mitochondrial fission can be uncoupled from cytochrome C release.由Bax或Bak诱导的线粒体裂变可与细胞色素C释放解偶联。
Mol Cell. 2008 Aug 22;31(4):570-585. doi: 10.1016/j.molcel.2008.08.002.
8
Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization.Opa1介导的嵴开放依赖于Bax/Bak和BH3,是细胞凋亡所必需的,且不依赖于Bak寡聚化。
Mol Cell. 2008 Aug 22;31(4):557-569. doi: 10.1016/j.molcel.2008.07.010. Epub 2008 Aug 7.
9
Mitochondrial dynamics and apoptosis.线粒体动力学与细胞凋亡。
Genes Dev. 2008 Jun 15;22(12):1577-90. doi: 10.1101/gad.1658508.
10
SLP-2 interacts with prohibitins in the mitochondrial inner membrane and contributes to their stability.SLP-2 在线粒体内膜中与抑制素相互作用,并有助于其稳定性。
Biochim Biophys Acta. 2008 May;1783(5):904-11. doi: 10.1016/j.bbamcr.2008.02.006. Epub 2008 Feb 20.

Targeting bioenergetics to enhance cancer chemotherapy: mitochondria SLP into apoptosis.

作者信息

Khatri Shikha, Plas David R

机构信息

Department of Cancer and Cell Biology, Vontz Center for Molecular Studies, 3125 Eden Ave., Cincinnati, OH 45267, USA.

出版信息

Cancer Biol Ther. 2009 Sep;8(17):1659-61. doi: 10.4161/cbt.8.17.9456. Epub 2009 Sep 7.

DOI:10.4161/cbt.8.17.9456
PMID:19633429
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2903429/
Abstract
摘要