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立体定向放射治疗外周非小细胞肺癌后的胸壁疼痛和肋骨骨折。

Chest wall pain and rib fracture after stereotactic radiotherapy for peripheral non-small cell lung cancer.

作者信息

Voroney Jon-Paul J, Hope Andrew, Dahele Max R, Purdie Thomas G, Franks Kevin N, Pearson Shannon, Cho John B C, Sun Alex, Payne David G, Bissonnette Jean-Pierre, Bezjak Andrea, Brade Anthony M

机构信息

Department of Radiation Oncology, Tom Baker Cancer Centre Alberta, Canada.

出版信息

J Thorac Oncol. 2009 Aug;4(8):1035-7. doi: 10.1097/JTO.0b013e3181ae2962.

DOI:10.1097/JTO.0b013e3181ae2962
PMID:19633478
Abstract

Stereotactic body radiotherapy is an emerging treatment option for peripheral non-small cell lung cancer in medically inoperable patients. With high dose per fraction radiotherapy, late side effects are of possible concern. In our initial cohort of 42 patients treated with 54 to 60 Gy in three fractions, nine patients have rib fracture. The median dose to rib fracture sites was 46 to 50 Gy, depending on the method of dose calculation. We describe a typical case of poststereotactic radiotherapy rib fracture and present dosimetric analysis of patients with rib fracture.

摘要

立体定向体部放射治疗是医学上无法手术的外周非小细胞肺癌患者的一种新兴治疗选择。采用高剂量分次放疗时，可能会担心出现晚期副作用。在我们最初的42例接受54至60 Gy分三次照射治疗的患者队列中，有9例发生肋骨骨折。根据剂量计算方法，肋骨骨折部位的中位剂量为46至50 Gy。我们描述了一例立体定向放疗后肋骨骨折的典型病例，并对肋骨骨折患者进行了剂量学分析。

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