Wang Y
Zhonghua Yi Xue Za Zhi. 1990 Dec;70(12):673-5, 46.
Nerve regeneration through a vascularized muscle autograft was investigated in Sprague-Dawley rats. The electrophysiological evaluation, progressive ultrastructural observation and advanced image analysis system were employed to asses the nerve regeneration process at selected intervals postoperatively. The regenerating axons concentrated into bundles to establish 'Regenerating Nerve Units', in contact with the inner or outer surface of the muscle basement membrane. Regeneration through a vascularized muscle graft was equivalent to autogenous nerve graft. The feasible use of free muscle transfer or transplantation is also discussed. It is concluded that vascularized muscle graft can facilitate and guide the regeneration, especially in clinical repair of large gaps of a major nerve.
在Sprague-Dawley大鼠中研究了通过带血管蒂自体肌移植进行神经再生的情况。采用电生理评估、渐进性超微结构观察和先进的图像分析系统，在术后选定的时间间隔评估神经再生过程。再生轴突聚集形成束，以建立“再生神经单元”，与肌肉基底膜的内表面或外表面接触。通过带血管蒂肌移植的再生与自体神经移植相当。还讨论了游离肌肉转移或移植的可行性应用。得出的结论是，带血管蒂肌移植可以促进和引导神经再生，特别是在主要神经大缺损的临床修复中。
