Vanhille P, Dequiedt P, Lelievre G, Gosselin B, Tacquet A
Sem Hop. 1977 May 9;53(18-19):1037-44.
The concept of acute renal failure with anuria due to malignant nephro-angiosclerosis, is uncommon. We report two cases and compare them with others in the world literature. Knowledge of this disease entity is of triple interest: In diagnosis and classification in the field of acute vascular nephropathy with anuria. We cannot emphasise too much the interest of early renal biopsy after correction of abnormal blood pressure. In physiopathology, these malignant nephro-angioscleroses give rise to hypertension of pressor type with high renin levels. Finally therapeutic, for there exist drugs adapted to this type of hypertension. The association of acute renal failure and malignant nephro-angiosclerosis should be treated as an emergency, to avoid the passage to terminal and irreversible renal failure.
恶性肾血管硬化导致急性肾衰竭伴无尿的概念并不常见。我们报告两例病例,并将它们与世界文献中的其他病例进行比较。了解这种疾病实体有三个方面的意义:在急性血管性肾病伴无尿领域的诊断和分类中。我们再怎么强调纠正血压异常后早期肾活检的重要性都不为过。在病理生理学方面,这些恶性肾血管硬化会引发肾素水平升高的加压型高血压。最后在治疗方面,因为有适用于这种类型高血压的药物。急性肾衰竭与恶性肾血管硬化的关联应作为紧急情况处理,以避免发展为终末期不可逆肾衰竭。