Corrigan Damion K, Piletsky Sergey, McCrossen Sean
Cranfield Health, Cranfield University, Silsoe, Beds, United Kingdom.
PDA J Pharm Sci Technol. 2009 Mar-Apr;63(2):184-93.
This article compares the technical performances of several different commercially available swabbing materials for the purpose of cleaning verification. A steel surface was soiled with solutions of acetaminophen, nicotinic acid, diclofenac, and benzamidine and wiped with each swabbing material. The compounds were extracted with water or ethanol (depending on polarity of analyte) and their concentration in extract was quantified spectrophotometrically. The study also investigated swab debris on the wiped surface. The swab performances were compared and the best swab material was identified.
本文为进行清洁验证，比较了几种不同市售擦拭材料的技术性能。用对乙酰氨基酚、烟酸、双氯芬酸和苯甲脒溶液污染钢表面，并用每种擦拭材料进行擦拭。化合物用水或乙醇提取（取决于分析物的极性），并通过分光光度法定量提取物中它们的浓度。该研究还调查了擦拭表面上的拭子碎屑。比较了拭子性能并确定了最佳擦拭材料。
