Strosberg Jonathan R, Hammer Gary D, Doherty Gerard M
University of Michigan School of Medicine, Ann Arbor, Michigan 48109, USA.
J Natl Compr Canc Netw. 2009 Jul;7(7):752-8; quiz 759. doi: 10.6004/jnccn.2009.0051.
Adrenocortical carcinomas (ACCs) are rare tumors that arise from the cortex of the adrenal gland with an incidence 1 to 2 per million. The rarity of this tumor translates into a paucity of experience in managing patients in most medical centers. Because clinical series are small and prospective evaluation of treatment strategies is limited, the current state of knowledge is strongly influenced by expert consensus opinion from a few medical centers specializing in ACCs. This article describes the basic diagnostic and prognostic issues in adrenal cancer management, and presents detailed rationales for therapeutic management.
肾上腺皮质癌（ACC）是一种罕见的肿瘤，起源于肾上腺皮质，发病率为百万分之一至二。这种肿瘤的罕见性导致大多数医疗中心在管理此类患者方面经验不足。由于临床病例系列较小且对治疗策略的前瞻性评估有限，目前的知识状况在很大程度上受到少数专门治疗ACC的医疗中心的专家共识意见的影响。本文描述了肾上腺癌管理中的基本诊断和预后问题，并提出了治疗管理的详细理论依据。
