Leung Kevin K, Heitzman Joseph, Madan Anand
Department of Gastroenterology, The University of Texas Health Science Center, Houston, TX 77030, USA.
Saudi J Gastroenterol. 2009 Jul-Sep;15(3):196-8. doi: 10.4103/1319-3767.54745.
Squamous cell carcinoma (SCC) of the rectum is an extremely rare malignancy, accounting for 0.1-0.2% of rectal malignancies. It is associated with ulcerative colitis, prior radiation, schistosomiasis, ovarian cancer, endometrial cancer, human papilloma virus, colocutaneous fistulas and colonic duplication. Prior reported cases of SCC of the rectum have involved treatment with brachytherapy and external beam radiation. This case is particularly interesting because of the remote exposure of radiation (21 years previously) and the subsequent development of SCC of the rectum. Although extremely rare, SCC of the rectum can occur decades after radiation exposure.
直肠鳞状细胞癌（SCC）是一种极为罕见的恶性肿瘤，占直肠恶性肿瘤的0.1 - 0.2%。它与溃疡性结肠炎、既往放疗、血吸虫病、卵巢癌、子宫内膜癌、人乳头瘤病毒、结肠皮肤瘘和结肠重复畸形有关。既往报道的直肠SCC病例涉及近距离放疗和外照射治疗。该病例特别有趣，因为有远距离放疗暴露史（21年前），随后发生了直肠SCC。尽管极为罕见，但直肠SCC可在放疗暴露数十年后发生。
