del Romeral L Munoz, Stillson C, Lesh M, Dae M, Botvinick Elias
Division of Heart Failure and Pulmonary Hypertension, Alta Bates Hospital, Berkeley, CA, USA.
J Nucl Cardiol. 2009 Sep-Oct;16(5):792-800. doi: 10.1007/s12350-009-9114-9. Epub 2009 Jul 28.
Phase imaging derived from equilibrium radionuclide angiography presents the ventricular contraction sequence. It has been widely but only indirectly correlated with the sequence of electrical myocardial activation.
We sought to determine the specific relationship between the sequence of phase progression and the sequence of myocardial activation, contraction and conduction, in order to document a noninvasive method that could monitor both.
In 7 normal and 9 infarcted dogs, the sequence of phase angle was correlated with the epicardial activation map in 126 episodes of sinus rhythm and pacing from three ventricular sites.
In each episode, the site of earliest phase angle was identical to the focus of initial epicardial activation. Similarly, the serial contraction pattern by phase image analysis matched the electrical epicardial activation sequence completely or demonstrated good agreement in approximately 85% of pacing episodes, without differences between normal or infarct groups.
A noninvasive method to accurately determine the sequence of contraction may serve as a surrogate for the associated electrical activation sequence or be applied to identify their differences.
源自平衡放射性核素血管造影的相位成像呈现心室收缩序列。它已被广泛应用，但仅与心肌电激动序列存在间接关联。
我们试图确定相位进展序列与心肌激动、收缩及传导序列之间的具体关系，以便记录一种能够同时监测两者的非侵入性方法。
在7只正常犬和9只梗死犬中，在126次窦性心律及从三个心室部位起搏的过程中，将相位角序列与心外膜激动图相关联。
在每次记录中，最早相位角的部位与初始心外膜激动的焦点相同。同样，通过相位图像分析得出的连续收缩模式与心外膜电激动序列完全匹配，或在大约85%的起搏记录中显示出良好的一致性，正常组和梗死组之间无差异。
一种准确确定收缩序列的非侵入性方法可作为相关电激动序列的替代指标，或用于识别它们之间的差异。
