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盘基网柄菌芽孢前特异性抗原的核磁共振归属——一种细胞表面黏附糖蛋白

NMR assignment of prespore specific antigen--a cell surface adhesion glycoprotein from Dictyostelium discoideum.

作者信息

Swarbrick James D, Cubeddu Liza, Ball Graham E, Curmi Paul M G, Gooley Andrew A, Williams Keith L, Mabbutt Bridget C

机构信息

Department of Chemistry & Biomolecular Sciences, Macquarie University, Sydney, NSW, Australia.

出版信息

Biomol NMR Assign. 2009 Jun;3(1):1-3. doi: 10.1007/s12104-008-9126-4. Epub 2008 Nov 7.

Abstract

Presopore-specific antigen (PsA) is a cell surface glycoprotein of the cellular slime mould Dictyostelium discoidum implicated in cell adhesion. The (15)N, (13)C and (1)H chemical shift assignments of PsA were determined from multidimensional, multinuclear NMR experiments. Resonance assignments have been made for both the N-terminal globular domain and its attached O-glycosylated PTVT linker motif.

摘要

前孢子特异性抗原(PsA)是盘基网柄菌细胞表面的一种糖蛋白,与细胞黏附有关。通过多维多核核磁共振实验确定了PsA的(15)N、(13)C和(1)H化学位移归属。已对N端球状结构域及其连接的O-糖基化PTVT连接基序进行了共振归属。

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