Ota Takahiro, Kamada Kyousuke, Aoki Shigeki, Saito Nobuhito
Department of Neurosurgery, The University of Tokyo, Tokyo, Japan.
Br J Neurosurg. 2009 Aug;23(4):406-11. doi: 10.1080/02688690902838815.
We performed functional MRI with several semantic tasks to visualize parietal lobe functions. Twenty subjects were studied, including 9 normal controls and 11 patients with brain lesions. The calculation task was to simply add 3 numbers projected on a screen. Functional MRI showed the active pixels in the bilateral interparietal sulcus (especially the dominant side) and mean values and standard deviation of left/right ratios of active pixels in the interparietal sulcus were 1.63 +/- 0.57 in normal controls, and 1.64 +/- 0.72 in neurosurgical patients. In 3 patients, postoperative functional MRI well reflected sequential changes of their calculation ability. This technique is simple to apply to evaluate the severity of dyscalculia not only for parietal lobe lesions, but also for other diseases, such as developmental dyscalculia, autism and dementia.
我们进行了功能性磁共振成像（functional MRI），采用多种语义任务来观察顶叶功能。共研究了20名受试者，其中包括9名正常对照者和11名脑损伤患者。计算任务是简单地将屏幕上显示的3个数字相加。功能性磁共振成像显示双侧顶内沟（尤其是优势侧）出现激活像素，正常对照者顶内沟激活像素的左右比率均值及标准差分别为1.63±0.57，神经外科患者为1.64±0.72。在3例患者中，术后功能性磁共振成像很好地反映了其计算能力的连续变化。该技术不仅适用于评估顶叶病变所致失算症的严重程度，也适用于评估其他疾病，如发育性失算症、自闭症和痴呆症等所致失算症的严重程度，且应用简便。
