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用于鞍结节脑膜瘤的额底半球间入路;长期视觉结果

Fronto-basal interhemispheric approach for tuberculum sellae meningiomas; long-term visual outcome.

作者信息

Ganna Ahmed, Dehdashti Amir R, Karabatsou Konstantina, Gentili Fred

机构信息

Division of Neurosurgery, Toronto Western Hospital, UHN, University of Toronto, Ontario, Canada.

出版信息

Br J Neurosurg. 2009 Aug;23(4):422-30. doi: 10.1080/02688690902968836.

Abstract

We report our experience with the treatment of tuberculum sellae meningiomas using the fronto-basal interhemispheric approach. A retrospective analysis was performed on a series of 24 patients with tuberculum sellae meningiomas who were operated between March 2000 and January 2007. Patients' presenting symptoms, radiological images, operative reports, and clinical follow-up data were reviewed with special consideration for visual outcome. Visual deterioration was the presenting symptom in all patients, followed by headache in 9 patients (37.5%). The average duration of visual symptoms was 17.6 months. The average tumor diameter was 2.63 cm; encasement of the carotid artery was identified in 7 patients (29%). Complete tumor removal was achieved in 21 patients (87.5%). Mean follow-up period was 52 months. Vision improved in 19 patients (79%), remained stable in 4 (17%) and deteriorated in 1 patient (4%). The degree of tumor removal or visual outcome were both unrelated to the tumor size (p = 0.2 and p = 0.6 respectively). While the degree of preoperative visual deficit did not affect the visual improvement rate in the whole group (p = 0.9), those patients with improvement to good functional vision (>20/40) after the surgery, had a less severe preoperative deficit (p < 0.001). The most common complication was anosmia (29.1%) and there was no mortality. The frontobasal interhemispheric approach is safe and provides a direct anatomical approach to tuberculum sellae meningiomas with relatively low incidence of complications. Patients with improved vision to good functional level had a better preoperative visual status.

摘要

我们报告了使用额底经半球间入路治疗鞍结节脑膜瘤的经验。对2000年3月至2007年1月期间接受手术的24例鞍结节脑膜瘤患者进行了回顾性分析。回顾了患者的临床表现、影像学图像、手术报告和临床随访数据,并特别关注视觉结果。所有患者的首发症状均为视力减退,其次是9例患者(37.5%)出现头痛。视觉症状的平均持续时间为17.6个月。肿瘤平均直径为2.63 cm;7例患者(29%)发现颈动脉被包绕。21例患者(87.5%)实现了肿瘤全切。平均随访期为52个月。19例患者(79%)视力改善,4例(17%)视力稳定,1例患者(4%)视力恶化。肿瘤切除程度或视觉结果均与肿瘤大小无关(分别为p = 0.2和p = 0.6)。虽然术前视力缺损程度在整个组中不影响视力改善率(p = 0.9),但术后视力改善至良好功能视力(>20/40)的患者术前缺损程度较轻(p < 0.001)。最常见的并发症是嗅觉丧失(29.1%),无死亡病例。额底经半球间入路安全,为鞍结节脑膜瘤提供了直接的解剖入路,并发症发生率相对较低。视力改善至良好功能水平的患者术前视觉状态较好。

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