Prescrire Int. 2009 Jun;18(101):122.
In addition to the adverse effects shared by all cytotoxic drugs, gemcitabine carries a risk of Lyell syndrome and other related cutaneous disorders, various types of liver damage (sometimes with positive rechallenge), and arterial thrombosis sometimes associated with necrosis.
除了所有细胞毒性药物共有的不良反应外,吉西他滨还存在发生中毒性表皮坏死松解症及其他相关皮肤疾病、各类肝损伤(有时再次用药呈阳性反应)的风险,以及有时与坏死相关的动脉血栓形成。