Chen Wen-Hao, Qi Huan-Yang, Shi Yan-Ping
State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, People's Republic of China.
J Nat Prod. 2009 Aug;72(8):1410-3. doi: 10.1021/np900199x.
Phytochemical investigation of the aerial parts of Oxytropis falcata led to the isolation of three new 24-hydroxyoleanane-type triterpenes (1-3), seven known analogues (4-10), and two rare sesquiterpenoids (12, 13). Compounds 6 and 12 were isolated as new natural products. Triterpenes (5, 6, 8, 11) were isolated from the roots of O. falcata. The structures and relative configurations of these compounds were elucidated by spectroscopic analyses, including 1D and 2D NMR spectroscopy and mass spectrometry, and by comparison of their NMR data with those of related compounds. Single-crystal X-ray diffraction analyses confirmed the structures of 1-4, and the absolute configuration of 3 was evidenced by the incorporation of DMSO (crystallization solvent) in the crystal lattice.
对镰形棘豆地上部分进行植物化学研究，分离得到了三种新的24-羟基齐墩果烷型三萜（1-3）、七种已知类似物（4-10）以及两种罕见的倍半萜（12、13）。化合物6和12作为新的天然产物被分离得到。三萜（5、6、8、11）是从镰形棘豆的根中分离得到的。这些化合物的结构和相对构型通过光谱分析得以阐明，包括一维和二维核磁共振光谱以及质谱分析，并且通过将它们的核磁共振数据与相关化合物的数据进行比较来确定。单晶X射线衍射分析确定了1-4的结构，3的绝对构型通过在晶格中引入二甲基亚砜（结晶溶剂）得以证实。
