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局部麻醉下的皮质映射与切除术辅助低级别和中级别胶质瘤手术

Cortical mapping and resection under local anaesthetic as an aid to surgery of low and intermediate grade gliomas.

作者信息

Walsh A R, Schmidt R H, Marsh H T

机构信息

Department of Neurosurgery, Atkinson Morley's Hospital, London, UK.

出版信息

Br J Neurosurg. 1990;4(6):485-91. doi: 10.3109/02688699008993797.

DOI:10.3109/02688699008993797
PMID:1963787
Abstract

We report four cases of the use of per-operative cortical mapping during craniotomy under local anaesthesia to define the relationship between the glioma and speech and somatosensory cortex. This enabled a radical subtotal (two cases) or an apparent total (two cases) excision of the tumour close to somatosensory and speech cortex with no permanent neurological deficit. Use of this technique allows radical excision of intrinsic low and intermediate grade gliomas that would otherwise be considered unexcisable and may lead to an improved survival.

摘要

我们报告了4例在局部麻醉下开颅手术期间使用术中皮质图谱来确定神经胶质瘤与言语及躯体感觉皮层之间关系的病例。这使得在靠近躯体感觉和言语皮层处对肿瘤进行根治性次全切除(2例)或明显全切除(2例),且无永久性神经功能缺损。使用该技术能够根治性切除原本被认为无法切除的原发性低级别和中级别的神经胶质瘤,并可能提高生存率。

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Cortical mapping and resection under local anaesthetic as an aid to surgery of low and intermediate grade gliomas.局部麻醉下的皮质映射与切除术辅助低级别和中级别胶质瘤手术
Br J Neurosurg. 1990;4(6):485-91. doi: 10.3109/02688699008993797.
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Cortical mapping and local anaesthetic resection as an aid to surgery of low and intermediate grade gliomas.皮质图谱和局部麻醉下切除辅助低级别和中级别胶质瘤手术
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Intraoperative mapping during repeat awake craniotomy reveals the functional plasticity of adult cortex.重复清醒开颅手术中的术中图谱显示了成人皮质的功能可塑性。
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Cortical localization of temporal lobe language sites in patients with gliomas.胶质瘤患者颞叶语言区的皮质定位
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Craniotomy under local anesthesia and monitored conscious sedation for the resection of tumors involving eloquent cortex.在局部麻醉和监测下的清醒镇静状态下行开颅手术,以切除累及功能区皮质的肿瘤。
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引用本文的文献

1
New concepts in surgery of WHO grade II gliomas: functional brain mapping, connectionism and plasticity--a review.世界卫生组织二级胶质瘤手术的新概念:功能脑图谱、连接主义与可塑性——综述
J Neurooncol. 2006 Aug;79(1):77-115. doi: 10.1007/s11060-005-9109-6. Epub 2006 Apr 11.
2
Contribution of intraoperative electrical stimulations in surgery of low grade gliomas: a comparative study between two series without (1985-96) and with (1996-2003) functional mapping in the same institution.术中电刺激在低级别胶质瘤手术中的作用:同一机构两个系列(1985 - 1996年无功能图谱,1996 - 2003年有功能图谱)的比较研究
J Neurol Neurosurg Psychiatry. 2005 Jun;76(6):845-51. doi: 10.1136/jnnp.2004.048520.