Lei Y H
Cancer Hospital, Chinese Academy of Medical Sciences, Beijing.
Zhonghua Zhong Liu Za Zhi. 1990 Nov;12(6):469-71.
A retrospective analysis of 73 patients with glioblastoma multiforme treated with surgery plus radiotherapy (63 cases) or surgery alone (10 cases) showed that the 5-year survival was 16% versus 0% and the median survival time was 14 versus 5 months. The median survival time in patients receiving postoperative radiotherapy was almost 3 times as long as that in patients treated with surgery alone. The difference in survival was insignificant between patients treated with a local extended field and those with whole brain plus local irradiation. The age, sex, course of disease, extent of operation and dose of irradiation are the factors influencing prognosis.
对73例多形性胶质母细胞瘤患者进行回顾性分析,这些患者接受了手术加放疗(63例)或单纯手术(10例)治疗,结果显示5年生存率分别为16%和0%,中位生存时间分别为14个月和5个月。接受术后放疗患者的中位生存时间几乎是单纯手术治疗患者的3倍。局部扩大野放疗患者与全脑加局部照射患者的生存差异不显著。年龄、性别、病程、手术范围和照射剂量是影响预后的因素。