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[多形性胶质母细胞瘤的手术与放疗联合治疗——73例报告]

[Combined surgery and radiotherapy of glioblastoma multiforme--report of 73 cases].

作者信息

Lei Y H

机构信息

Cancer Hospital, Chinese Academy of Medical Sciences, Beijing.

出版信息

Zhonghua Zhong Liu Za Zhi. 1990 Nov;12(6):469-71.

PMID:1963841
Abstract

A retrospective analysis of 73 patients with glioblastoma multiforme treated with surgery plus radiotherapy (63 cases) or surgery alone (10 cases) showed that the 5-year survival was 16% versus 0% and the median survival time was 14 versus 5 months. The median survival time in patients receiving postoperative radiotherapy was almost 3 times as long as that in patients treated with surgery alone. The difference in survival was insignificant between patients treated with a local extended field and those with whole brain plus local irradiation. The age, sex, course of disease, extent of operation and dose of irradiation are the factors influencing prognosis.

摘要

对73例多形性胶质母细胞瘤患者进行回顾性分析,这些患者接受了手术加放疗(63例)或单纯手术(10例)治疗,结果显示5年生存率分别为16%和0%,中位生存时间分别为14个月和5个月。接受术后放疗患者的中位生存时间几乎是单纯手术治疗患者的3倍。局部扩大野放疗患者与全脑加局部照射患者的生存差异不显著。年龄、性别、病程、手术范围和照射剂量是影响预后的因素。

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