Isaacs David, Hazany Saman, Gamst Anthony, Stark Paul, Mahmud Ehtisham
Department of Radiology, University of California San Diego Medical Center, San Diego, CA, USA.
J Comput Assist Tomogr. 2009 Jul-Aug;33(4):513-6. doi: 10.1097/RCT.0b013e3181949b19.
To identify and measure the coronary sinus (CS) in patients with and without pulmonary artery hypertension (PAH) using chest computed tomography (CT).
Using a 4-channel GE LightSpeed CT scanner, nongated axial chest CT images were obtained after intravenous injection of contrast material. Catheterization of the right side of the heart was performed in patients with known or suspected PAH.
The CS was identified in all 60 patients (mean +/- SD, 60.5 +/- 17.5 years; 45% men) without PAH (control group) (mean +/- SD, diameter 7.05 +/- 1.90 mm). In 24 patients (9 men; average age +/- SD, 54.1 +/- 14.5 years) with known or suspected PAH (study group), pulmonary artery (PA) pressures were increased; the CS was dilated (mean +/- SD, 9.4 +/- 4. 2 mm); and its size correlated with right atrial pressure (r = 0.358, P = 0.061), mean PA pressure (r = 0.568, P = 0.005), systolic PA pressure (r = 0.375, P = 0.071), and diastolic PA (r = 0.561, P = 0.004).
The CS is routinely visualized and measurable on chest CT. In patients with PAH, CS dilation is associated with increased PA pressures.
使用胸部计算机断层扫描(CT)识别并测量有无肺动脉高压(PAH)患者的冠状窦(CS)。
使用4通道GE LightSpeed CT扫描仪,静脉注射造影剂后获取非门控胸部CT轴位图像。对已知或疑似PAH的患者进行右心导管检查。
在所有60例无PAH的患者(对照组)中均识别出CS(平均±标准差,60.5±17.5岁;45%为男性)(平均±标准差,直径7.05±1.90 mm)。在24例已知或疑似PAH的患者(研究组)中(9例男性;平均年龄±标准差,54.1±14.5岁),肺动脉(PA)压力升高;CS扩张(平均±标准差,9.4±4.2 mm);其大小与右心房压力(r = 0.358,P = 0.061)、平均PA压力(r = 0.568,P = 0.005)、收缩期PA压力(r = 0.375,P = 0.071)和舒张期PA(r = 0.561,P = 0.004)相关。
CS在胸部CT上可常规显示并测量。在PAH患者中,CS扩张与PA压力升高相关。