He Zhi Zhu, Liu Jing
Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, P.O. Box 2711, Beijing 100190, China.
J Biomech Eng. 2009 Jul;131(7):074502. doi: 10.1115/1.3142978.
In this article, the microscale ice crystal growth behavior under electrostatic field is investigated via a phase field method, which also incorporates the effects of anisotropy and thermal noise. The multiple ice nuclei's competitive growth as disclosed in existing experiments is thus successfully predicted. The present approach suggests a highly efficient theoretical tool for probing into the freeze injury mechanisms of biological material due to ice formation during cryosurgery or cryopreservation process when external electric field was involved.
在本文中,通过相场方法研究了静电场下的微观冰晶生长行为,该方法还考虑了各向异性和热噪声的影响。从而成功预测了现有实验中所揭示的多个冰核的竞争生长。本方法为探究在涉及外部电场的冷冻手术或冷冻保存过程中,生物材料因结冰而产生的冷冻损伤机制提供了一种高效的理论工具。