Inoue T, Nakamura T, Katagiri D, Hoshino T, Tada M, Shibata M, Hinoshita F
Division of Nephrology, International Medical Center of Japan, Tokyo, Japan.
Clin Nephrol. 2009 Aug;72(2):151-5. doi: 10.5414/cnp72151.
A 55-year-old Japanese woman with microscopic polyangiitis suffered repeated disturbance of consciousness and gastrointestinal bleeding. These problems were initially attributed to microscopic polyangiitis, but hereditary hemorrhagic telangiectasia was finally identified by further workup. Both microscopic polyangiitis and hereditary hemorrhagic telangiectasia are blood vessel-related diseases inducing similar symptoms. To our knowledge, this is the first observation of microscopic polyangiitis and hereditary hemorrhagic telangiectasia in the same patient. From a literature review of the clinical and pathologic manifestations of these diseases, a positive association may exist between the two diseases.
一名55岁患有显微镜下多血管炎的日本女性反复出现意识障碍和胃肠道出血。这些问题最初被归因于显微镜下多血管炎，但通过进一步检查最终确诊为遗传性出血性毛细血管扩张症。显微镜下多血管炎和遗传性出血性毛细血管扩张症均为血管相关疾病，可引发相似症状。据我们所知，这是首次在同一患者身上观察到显微镜下多血管炎和遗传性出血性毛细血管扩张症。通过对这些疾病的临床和病理表现进行文献回顾，发现这两种疾病之间可能存在正相关。
