Lazzari G B, Monteverdi A M, Adami O, Pezzarossa E
Divisione di Dermatologia, Ospedale Civile, Cremona.
G Ital Dermatol Venereol. 1990 Sep;125(9):XXXVII-XLII.
The therapeutic effectiveness and the tolerability of a collagenase-chloramphenicol ointment were studied on a group of 20 patients (mean age 73.4 +/- 13.6 years, range 25-88 years) with lower limb ulcerations of various origin. The ointment proved capable of favourably influencing the debridment and the healing process of these lesions. Statistically significant improvements were observed after days of treatment for debridment, inflammation and granulation, after eight days for the lesion size and after ten days for epithelization. Tolerability was very good.
对一组20例（平均年龄73.4±13.6岁，范围25 - 88岁）不同病因的下肢溃疡患者，研究了胶原酶 - 氯霉素软膏的治疗效果和耐受性。结果表明该软膏能够对这些损伤的清创和愈合过程产生有利影响。在治疗清创、炎症和肉芽形成方面，治疗数天后观察到有统计学意义的改善；在损伤大小方面，8天后有改善；在上皮形成方面，10天后有改善。耐受性非常好。
